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NC State University

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research lab

"To determine what the genes do, you must mimic nature’s precision in turning genes on and off."

Drs. Yoder and Deiters have received a $1.4 million NIH grant to develop a series of “photo-switchable” compounds that will allow scientists to turn individual genes on and off within zebrafish embryos.
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One Medicine

Rudolf Virchow

"Between animal and human medicine there is no dividing line – nor should there be." - Rudolf Virchow

Mission Statement

The mission of the CCMTR is to enhance collaborative, translational, interdisciplinary approaches for the comparative study of animal/human diseases . The members of the center recognize that complex issues affecting human and animal health are better addressed by interdisciplinary "one medicine" approaches that combine both clinical and non-clinical expertise. This includes interactions between different laboratories as well as interactions with private groups. The ability to provide unique training and expertise, and an environment of innovation facilitates the development of novel approaches to diagnose and treat disease. For more information contact the Center Director, Dr. Gregg Dean.

Discovery

Generate knowledge related to initiation, progression, and treatment of disease:

Comparative Medicine

  • Multiple species under study
  • Can match question of interest to most appropriate animal model
  • Benefits both human and animal health

Interdisciplinary Faculty

  • Clinical and non-clinical expertise gives the studies a balanced approach
  • Combination of disciplines as varied as oncology, biomaterials, and structural biochemistry
  • Clinical expertise in multiple areas

Partnerships

  • Ongoing collaboration with scientists at UNC, Duke, EPA, NIEHS, and others further enhancing discovery potential

Translation

From bench to clinic, more innovation to benefit the patient (animal & human):

Clinical Expertise

  • Broad clinical expertise across many animal species
  • Facilitates utilization of most appropriate animal model for drug/therapy development

Animals Models

  • Naturally occuring and induced models of human and animal disease
  • Multiple models in multiple species available

Interdisciplinary

  • Broad discipline representation facilitates rapid and more effective translation of scientific discoveries

Application

CCMTR & partners move translational advances from research clinics to the private sector:

Development & Commercialization

  • Move promising technology to the private sector through partnerships and licensing agreements
  • Assist interested industrial partners with development and testing of their discoveries through our experties in multiple animal models

Implementation

  • Move clinical therapeutic methods from research to utilization in clinics in collaboration with our partners in human and veterinary medicine

Regional Economic Development Assistance

  • Provide links to interested industries with economic development agencies to assist in moving innovation to the private sector