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CCTRP Faculty Members:

Staff Members:

  • Jim D. Brooks, MS, Laboratory Supervisor
  • Patty Routh, Research Specialist
  • Jim L. Yeatts, MS, Laboratory Research Specialist/Analytical Chemist

CCTRP Graduate Students/Trainess

  • Daniella Karadzovska, BS, Ph.D candidate
  • Alexcia Linthicum, BS, MS, Ph.D. Student
  • Lindsey Waltman, BS, MS, DVM/Ph.D. candidate

CCTRP Publications

Samberg ME, Loboa EG, Oldenburg SJ, Monteiro-Riviere NA. Silver nanoparticles do not influence stem cell differentiation but cause minimal toxicity. Nanomedicine 7(8): 1197-1209, 2012.

Gittard SD, Chen B, Xu H, Ovsianikov A, Chichkov BN, Monteiro-Riviere NA, Narayan     RJ.  The effects of geometry on skin penetration and failure of polymer microneedles. Journal of Adhesion Science and Technology DOI: 10.1080/01694243.2012.705101, 1-17, 2012.

Baynes R, Riviere J, Franz T, Monteiro-Riviere N, Lehman P, Peyrou M, Toutain P. Challenges obtaining a biowaiver for topical veterinary dosage forms. J Veterinary Pharmacology and Therapeutics. 35:103-114, 2012.

Riviere JE Leavens TL, Brooks JD, Monteiro-Riviere NA. Acute vascular effects of nanoparticle infusion in isolated perfused skin. Nanomedicine: Nanotechnology, Biology and Medicine 8:428-431, 2012.

Monteiro-Riviere NA, Linder KE, Inman AO, Saathoff JG, Xia XR, Riviere JE. Lack of hydroxylated fullerene toxicity after intravenous administration to female Sprague-Dawley rats. Journal of Toxicology and Environmental Health A. 75(7): 367-3673.

Skoog SA, Sumant A, Monteiro-Riviere NA, Narayan RJ. Ultrananocrystalline diamond-coated microporous silicon nitride membranes. JOM 64 (4): 520-525, 2012.

Monteiro-Riviere NA and Larese Filon F. Effects of Engineered Nanomaterials on Skin. In  Adverse Effects of Engineered Nanomaterials (Eds. B Fadeel, A. Pietroiusti, and A Shvedova), Elsevier, NY,  Chapter 11, 185- 207, 2012.

Prow TW, Monteiro-Riviere NA, Inman AO. Grice JE, Chen X, Zhao X, Sanchez WH, Gierden A, Kendall MA, Zvyagin AV, Erdmann D, Riviere JE, Roberts MS. Quantum dot penetration into viable human skin. Nanotoxicology 6:173-185, 2012.

Xia XR, Monteiro-Riviere NA, Mathur S, Xuefeng S, Xiao L, Oldernburg S, Fadeel S, Riviere JE. Mapping the surface adsorption forces of nanomaterials in biological systems. ACS Nano 5: 9074-9081, 2011.

Boehm RD, Miller PR, Hayes SL, Monteiro-Riviere NA, Narayan RJ. Modification of microneedles using inkjet printing.  American Institute of Physics Advances 1(2):22139, 2011

Saathoff JG, Inman AO, Xia XR, Riviere JE, Monteiro-Riviere NA. In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells. Toxicology In Vitro 25:2105-2112.

Monteiro-Riviere NA, Wiench K, Landsiedel R, Schulte S, Inman AO, Riviere JE. Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: an in vitro and in vivo study. Toxicological Sciences 123 (1) 264-280, 2011.

Monteiro-Riviere NA. Commentary on transcutaneous delivery. WIREs Nanomedicine and Nanobiotechnology 3: 439-440, 2011.

Zhang LW, Bäumer W, Monteiro-Riviere NA. Cellular uptake mechanisms and toxicity of quantum dots in dendritic cells. Nanomedicine 6 (5) 777-791, 2011.

Miller PR, Gittard SD, Edwards TL, Lopez DM, Xiao X, Wheeler DR, Monteiro-Riviere NA, Brozik SM, Polsky R, Narayan RJ. Integrated carbon fiber electrodes within hollow polymer microneedles for transdermal electrochemical sensing.  Biomicrofluidics 5:13415, 2011.

Hyde GK, Stewart SM, Scarel G, Parsons GN, Shih CC, Shih CM, Lin SJ, SU YY, Monteiro-Riviere NA, Narayan RJ.  Atomic layer deposition of titanium dioxide on cellulose acetate for enhanced hemostasis. Biotechnology Journal  6: 213-123, 2011.

Gittard SD, Miller PR, Boehm RD, Ovianikov A, Chichkov BN, Heisner J, Gordon J, Monteiro-Riviere NA, Narayan RJ. Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles. Faraday Discussions 149: 171-185, 2011.

Riviere JE, Brooks JD. Predicting Skin Permeability from Complex Chemical Mixtures: Dependency of Quantitative Structure Permeation Relationships on Biology of Skin Model Used. In Toxicological Sciences 119: 224-232, 2011.

Ghafourian T, Samaras EG, Brooks JD, Riviere JE. Validated models for predicting skin penetration from different vehicles. In European Journal of Pharmaceutical Sciences 41:612-616, 2010.

Samberg ME, Orndorff PE, Monteiro-Riviere NA.  Antibacterial efficacy of silver nanoparticles of different sizes, surface conditions and synthesis methods. Nanotoxicology 5:244-253, 2011.

Riviere JE, Inman AO, Monteiro-Riviere NA. Absorption, Penetration and Cutaneous Toxicity of Jet Fuels and Hydrocarbons Components. In Witten ML, Zeiger E, Ritchie GD (eds.) Jet Fuel Toxicology, CRC Press, Boca Raton, Fl, Chapter 7, 119-134, 2010. 

Ghafourian T, Samaras EG, Brooks JD, Riviere JE. Modelling the effects of mixture components on permeation through skin. In International Journal of Pharmaceutics. 398, pp.28-32, 2010.

Xia XR, Monteiro-Riviere NA, Riviere JE. An index for characterization of nanomaterials in biological systems. Nature Nanotechnology 5: 671-675, 2010.

Baynes RE, Riviere JE. Dermal Chemical Mixtures. Mixtures Toxicity. In Principles and Practice of Mixtures Toxicity. (Mumtaz MM, ed). Wiley-VCH Weinheim, Chapter 14, pp. 349-376, 2010.

Basak SC, Gute BD, Monteiro-Riviere NA, Witzmann FA: Characterization of          Toxicoproteomics Maps for Chemical Mixtures using Information Theoretic Approach. In Principles and Practice of Mixtures Toxicity. (Mumtaz MM, ed). Wiley-VCH Weinheim, Chapter 8, pp.215-234, 2010.   

Doraiswany A, Ovsianikov A, Gittard SD, Monteiro-Riviere NA, Crombez R, Montalvo E, Shen W, Cichkov BN, Narayan RJ. Fabrication of microneedles using two-photon polymerization for transdermal delivery of nanomaterials. J Nanoscience and Nanotechnology 10:6305-6312, 2010.

Narayan RJ, Adiga SP, Pellin MJ, Curtiss LA, Stafslien S, Chisholm B, Monteiro-Riviere NA, Brigmon RL, Elam JW.  Atomic layer deposition of nanoporous biomaterials. Materials Today 13:60-64, 2010.

Gittard SD, Ovsianikov A, Akar H, Chichkov BN, Monteiro-Riviere NA, Stafslien S, Chilsholm B, Shih CC, Shih CM, LinSJ, SuYY, Narayan RJ. Two-photon polymerization-micromolding of polyethylene glycol-gentamicin sulfate microneedles. Advanced Engineering Biomaterials 12 (4), B77-B82, 2010.

Riviere JE, Monteiro-Riviere NA.  Toxicokinetics: Dermal Exposure and Absorption of    Chemicals and Nanomaterials. In Comprehensive Toxicology, 2nd Ed. (McQueen C, ed). Elsevier, NY, Vol. 1. Chapter 1.05: 111-122, 2010.

Xia XR, Monteiro-Riviere NA, Riviere JE. Intrinsic biological property of colloidal fullerene nanoparticle (nC60): Lack of lethality after high dose exposure to human epidermal and bacterial cells. Toxicology Letters 197: 128-134, 2010.

Leavens TL, Xia XR, Lee HA, Monteiro-Riviere NA, Brooks JD, Riviere JE: Evaluation of perfused porcine skin as a model system to quantitate tissue distribution of fullerene nanoparticles. Toxicology Letters 197:1-6, 2010.

Haslauer CM, Springer J, Harrysson OLA, Loboa EG, Monteiro-Riviere NA, Marcellin-Little DJ. In vitro biocompatibility of titanium alloy discs made using direct metal fabrication. Medical Engineering and Physics 32:645-652, 2010.

Riviere JE. New Technologies for Application to Veterinary Therapeutics. In Comparative and Veterinary Pharmacology. Handbook of Experimental Pharmacology 199, (Eds.F. Cunningham, J. Elliott, P.Lees).  Springer, NY, 191-210, 2010.

Riviere JE. Dermal Absorption Modeling. In  Human Exposure to Pollutants via Dermal Absorption and Inhalation. Environmental Pollution Vol. 17( Eds. M. Lazaridis and I. Colbeck). Springer, UK, Chapter 7, 237-249, 2010.

Monteiro-Riviere NA, Oldenburg SJ, Inman AO. Interactions of aluminum nanoparticles with human epidermal keratinocytes. Journal of Applied  Toxicology 30:276-285, 2010.

Riviere JE, Brooks JD, Yeatts JL, Koivisto EL. Surfactant Effects on Skin Absorption of Model Organic Chemicals: Implications For Dermal Risk Assessment Studies. Journal of Toxicology and Environmental Health Part A, 73:725-737, 2010.

Narayan RJ,  Adiga SP, Pellin MJ, Curtiss LA, Hryn AJ, Stafslien S, Chisholm B, Shih CC, Shih CM, Lin SJ, Su YY, Jin C, Zhang J, Monteiro-Riviere NA, Elam JW. Atomic layer deposition-based functionalization of materials for medical and environmental health applications. Philosophical Transactions of The Royal Society A Mathematical, Physical & Engineering Sciences 368:2033-2064, 2010. 

Baynes RE, Vijay V. Dermal Absorption and Cutaneous Toxicity of Metalworking Fluids. In Toxicology of the Skin-Target Organ Series. (Ed. NA Monteiro-Riviere). Informa Healthcare, New York, NY, Vol 29, Chapter 24, 361-374, 2010.

Grissom RE, Abernathy CO, Monteiro-Riviere NA. Potential Arsenic Exposure Through Dermal Penetration. In Toxicology of the Skin-Target Organ Series. (Ed. NA Monteiro-Riviere). Informa Healthcare, New York, NY, Vol. 29, Chapter 23, 347-360, 2010.

Monteiro-Riviere NA and Baroli B.  Nanomaterial Penetration.  In Toxicology of the Skin-Target Organ Series. (Ed. NA Monteiro-Riviere). Informa Healthcare, New York, NY, Vol. 29, Chapter 22, 333-346, 2010.

Riviere JE. Basic Principles Involved in Quantifying the Dermal Absorption of Topically Applied Chemicals. In Toxicology of the Skin-Target Organ Series.  (Ed. NA Monteiro-Riviere). Informa Healthcare, New York, NY, Vol. 29, Chapter 5, 43-54, 2010.

Monteiro-Riviere NA. Structure and Function of Skin. In Toxicology of the Skin-Target Organ Series.  (Ed. NA Monteiro-Riviere). Informa Healthcare, New York, NY, Vol. 29, Chapter 1, 1-18, 2010.

Samberg ME, Oldenburg SJ, Monteiro-Riviere NA. Evaluation of silver nanoparticle toxicity in vivo skin and in vitro keratinocytes. Environmental Health Perspectives 118, 407-413, 2010.

Zhang LW, Monteiro-Riviere NA. Lectins modulate multi-walled carbon nanotubes cellular uptake in human epidermal keratinocytes. Toxicology In Vitro 24: 546-551, 2010.

Xia XR, Monteiro-Riviere NA, Riviere JE.  Skin penetration and kinetics of pristine fullerenes (C60) topically exposed in industrial organic solvents. Toxicology and Applied Pharmacology 242: 29-37, 2010.

Gittard SD, Narayan RJ, Jic C, Ovsianikov A, Chichkov BN, Monteiro-Riviere NA, Stafslien S, Chisholm B. Pulsed laser deposition of antimicrobial silver coating on Ormocer microneedles. Biofabrication 1:041001, 2009.

Gittard SD, Ovsianikov A, Monteiro-Riviere NA, Lusk J, Morel P, Minghetti P,Lenardi C,Chichkov BN, Narayan RJ. Fabrication of microneedles using a two-photon polymerization and micromolding process. Journal of Diabetes Science and Technology  3: 304-311, 2009.

Mason SE, Baynes RE, Almond GW, Riviere JE, Scheidt AB.  Pharmacology of tetracycline water medication in swine.   Journal of Animal Science 87: 3179-3186, 2009.

Zhang LW,  Yang J, Barron AR, Monteiro-Riviere NA.  Endocytic mechanisms and toxicity of  a functionalized fullerene in human cells. Toxicology Letters 191: 149-157, 2009.

Adiga S, Jin C, Curtiss LA, Monteiro-Riviere NA, Narayan RJ.  Nanoporous membranes for medical and biological applications. WIRES Nanomedicine and Nanobiotechnology 1:568-581, 2009.

Riviere JE, Monteiro-Riviere NA. Cutaneous Toxicology. In General and Applied Toxicology, (Eds. B. Ballentyne, T. Marrs, and T.  3rd Ed. Wiley: West Sussex, UK, Chapter 44, 1003-1015, 2009.

Monteiro-Riviere NA and Riviere JE Interaction of nanomaterials with skin: Aspects of absorption and biodistribution. Nanotoxicology 3(3):188-193, 2009.

Thomas K, Monteiro-Riviere N, Warheit D, Savage N. Evaluating the risks associated with nanomaterials. In The Oxford Handbook of Nanoscience and Technology, Frontiers and Advances.(Eds. AV Narlikar and YY Du).  Vol, III, Oxford University Press, Oxford, UK. Chapter 25, 888-906, 2009. 

Boehm R, Narayan RJ, Aggarwal R, Monteiro-Riviere NA, Lacour S. Stretchable diamond-like carbon microstructures for biomedical applications.  JOM 61: 46-51, 2009.

Vijay V, White EM, Kaminski Jr. MD, Riviere JE, Baynes RE.  Dermal permeation of biocides and aromatic chemicals in three generic formulations of metalworking fluids.  Journal of Toxicology and Environmental Health 72, 832-841, 2009.

Riviere JE, Brooks JD.  Determination of the effective dermal penetration barrier pH of porcine skin.  Journal of Veterinary Pharmacology and  Therapeutics. 32, 407-410, 2009.

Zhang LW, Monteiro-Riviere NA. Mechanisms of quantum dot nanoparticle cellular uptake. Toxicological Sciences 110: 138-155, 2009.

Gittard SD, Narayan RJ, Lusk J, Morel P Stockmans F, Ramsey M, Laverde C, Phillips J, Monteiro-Riviere NA, Ovsianikov A, Chichkov BN. Rapid prototyping of scaphoid and lunate bones. Biotechnology Journal 4:129-134, 2009.

Sumanasinghe RD, Monteiro-Riviere NA, Loboa EG. Expression of proinflammatory cytokines by human mesenchymal stem cells under cyclic tensile strain.  Journal of Cellular Physiology 219:77-83, 2009.

Lee HA, Leavens TL, Mason SE, Monteiro-Riviere NA, Riviere JE.  Comparison of. quantum dot biodistribution with a blood-flow-limited physiologically based pharmacokinetic model.  Nano Letters 794-799, 2009.

Smith GW, Davis JL, Baynes RE, Yeatts JL, Barlow BM, Riviere JE.  Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle.  Journal of the American Veterinary Association 234:245-248, 2009.

Monteiro-Riviere NA, Inman AO, Zhang LW. Limitations and relative utility of screening assays to asses engineered nanoparticle toxicity in a human cell line. Toxicology and Applied Pharmacology 234: 222-235, 2009.

Riviere JE:  Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots. WIRES Nanomedicine and Nanobiotechnology  1: (1), 26-34, 2009.

Elder A, Lynch I, Grieger K, Chan-Remillard S, Gatti A,Gnewuch H, Kenawy E, Korenstein R, Kuhlbusch T, Linker F, Matias S, Monteiro-Riviere N, Pinto V, Rudnitsky R, Savolainen K, Shvedova A. Human Health Risks of Engineered Nanomaterials. In Linkov I, Steevens J (eds.): Nanomaterials: Risks and Benefits. Springer, Dordrecht, Netherlands, 1-28, 2008.

Monteiro-Riviere NA, Zhang LW. Assessment of Quantum Dot Penetration into Skin in Different Species Under Different Mechanical Actions. In Linkov I, Steevens J (eds.): Nanomaterials: Risks and Benefits. Springer, Dordrecht, Netherlands, pp. 41-52, 2008.

Narayan RJ, Aggarwal R, Wei W, Jin C, Monteiro-Riviere NA, Crombez R, Shen W.  Mechanical and biological properties of nanoporous carbon membranes. Biomedical Materials 3: 034107, 2008. doi:10.1088/1748-6041/3/3/034107

Monteiro-Riviere NA: Dermatotoxicology. In Molecular and Biochemical Toxicology. (Eds. RC Smart and E Hodgson). 4th ed, Wiley &Sons, NJ, Chapter 35, 851-880, 2008.

 

 

 

O'Neill AT, Monteiro-Riviere NA, Walker GM: Characterization of microfluidic human epidermal keratinocyte culture. Cytotechnology 56:197-207, 2008.

Buur JL, Baynes RE, Riviere JE: Estimating meat withdrawal times in pigs exposed to melamine contaminated feed using a physiologically based pharmacokinetic model. Regulatory Toxicology and Pharmacology 51: 324-331, 2008.

Karakoti AS, Monteiro-Riviere NA, Aggarwal R, Davis JP, Narayan RJ, Self WT, McGinnis J, Seal S: Nanoceria as antioxidant: synthesis and biomedical applications. Journal of Material Sciences 60: 33-37, 2008.

Zhang LW, and Monteiro-Riviere NA: Assessment of quantum dot penetration into intact, tape stripped, abraded and flexed rat skin. Skin Pharmacology and Physiology 21:166-180, 2008.

Inman AO, Monteiro-Riviere NA, Riviere JE: Inhibition of jet fuel aliphatic hydrocarbon induced toxicity in human epidermal keratinocytes. Journal of Applied Toxicology 28: 543-553, 2008.

Zhang LW, Yu WW, Colvin VL, Monteiro-Riviere NA: Biological Interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes. Toxicology and Applied Pharmacology 228:200-211, 2008.

Yeatts JL, Baynes RE, Xia XR, Riviere JR: Application of linear salvation energy relationships to a custom-made polyaniline solid-phase microextraction fiber and three commercial fibers. Journal of Chromatography A 1188: 108-117, 2008.

Lin JY, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Zielinski J: Topical isoflavones provide effective photoprotection to skin. Photodermatology, Photoimmunology and Photomedicine 24:61-66, 2008.

Mason SE, Baynes RE, Buur JL, Riviere JE, Almond GW: Sulfamethazine water Medication Pharmacokinetics and Contamination in a Commercial Pig Production Unit. Journal of Food Protection 71: 584-589, 2008.

Baynes RE, Xia XR, Imran M, Riviere JE: Quantification of Chemical Mixture Interactions Modulating Dermal Absorption Using a Multiple Membrane Fiber Array. Chem. Res. Toxicol. 21: 591-599, 2008.

Smith GW, Davis JL, Tell LA, Webb AI, Riviere JE: Extralabel use of nonsteroidal ant-inflammatory drugs in cattle. Journal of the American Veterinary Medical Association 232:697-701, 2008.

Karakoti AS, Monteiro-Riviere NA, Aggarwal R, Davis JP, Narayan RJ, Self WT, McGinnis J, Seal S: Nanoceria as antioxidant: synthesis and biomedical applications. Journal of Material Sciences 60: 33-37, 2008.

Ardente AJ, Barlow BM, Burns P, Goldman R, Baynes RE: Vehicle effects on in vitro transdermal absorption of sevoflurane in the bullfrog, Rana catesbeiana. Environmental Toxicology and Pharmacology: 25: 373-379, 2008.

Rouse JG, Haslauer CM, Loboa EG, Monteiro-Riviere NA: Cyclic tensile strain increases interactions between human epidermal keratinocytes and quantum dot nanoparticles. Toxicology in Vitro: 22:491-497, 2008.

Baynes RB, Smith G, Mason SE, Barrett E, Barlow BM, Riviere JE: Pharmacokinetics of melamine in pigs following intravenous administration. Food and Chemical Toxicology 46: 1196-1200, 2008.

Roberts MS, Gierden A, Riviere JE, Monteiro-Riviere NA: Solvent and Vehicle Effects on the Skin. In Dermal Absorption and Toxicity Assessment. (Eds. MS Roberts and KA Walters). 2nd ed, Informa Healthcare, New York, NY, Chapter 24, 433-447, 2008.

Monteiro-Riviere NA, Baynes RE, Riviere JE: Animal Skin Morphology and Dermal Absorption. In Dermal Absorption and Toxicity Assessment. (Eds. MS Roberts and KA Walters). 2nd ed, Informa Healthcare, New York, NY, Chapter 2, 17-35, 2008.

Riviere JE: Isolated Perfused Porcine Skin Flap. In Dermatotoxicology. (Eds. H Zhai, KP Wilhelm, HI Maibach), 7th ed, CRC Press, New York, NY, Chapter 40, pp.347-358, 2008.

Riviere JE: Percutaneous Absorption of Complex Chemical Mixtures. In Dermatotoxicology. (Eds. H Zhai, KP Wilhelm, HI Maibach), 7th ed, CRC Press, New York, NY, Chapter 6, pp.63-70, 2008.

Monteiro-Riviere NA: Anatomical Factors that Affect Barrier Function. In Dermatotoxicology. (Eds. H Zhai, KP Wilhelm, HI Maibach), 7th ed, CRC Press, New York, NY, Chapter 4, pp.39-50, 2008.

Riviere JE, Xia XR, Baynes RE. Membrane coated fiber (MCF) array approach for predicting skin permeability of chemical mixtures from different vehicles. Toxicol. Sci. 99: 153-161, 2007.

McCullen SD, Stano KL, Stevens DR, Roberts WA, Monteiro-Riviere NA, Clarke LI, Gorga RE: Development, optimization and characterization of electrospun poly (lactic) nanofibers containing multi-walled carbon nanotubes. Journal of Applied Polymer Science 105: 1668-1678, 2007.

Xia XR, Baynes RE, Monteiro-Riviere NA, Riviere JE: A system coefficient approach for quantitative assessment of the solvent effects on membrane absorption from chemical mixtures. SAR QSAR Environmental Research 18(5): 579-593, 2007.

Needham ML, Webb AI, Baynes RE, Riviere JE, Craigmill AL, Tell LA: Current update on drugs for game bird species. Journal of the American Veterinary Medical Association 231: 1506-1508, 2007.

Baynes RE, Xia XR, Barlow BM, Riviere JE: Partitioning Behavior of Aromatic Components in Jet Fuel into Diverse Membrane-coated Fibers. Journal of Toxicology and Environmental Health 70: 1879-1887, 2007.

Vijay V, Yeatts JL, Riviere JE, Baynes RE: Predicting dermal permeability of biocides in commercial cutting fluids using a LSER approach. Toxicology Letters 175:34-43, 2007.

Riviere JE: The future of veterinary therapeutics: A glimpse towards 2030, The Veterinary Journal 174: 462-471, 2007.

Balbus JM, Maynard AD, Colvin VL, Castranova V, Daston GP, Denison RA, Dreher KL, Goering PL, Goldberg AM, Kulinowski KM, Monteiro-Riviere NA, Oberdorster G, Omenn GS, Pinkerton KE, Ramos KS, Rest KM, Sass JB, Silbergeld EK, and Wong BA: Meeting Report: Hazard Assessment for Nanoparticles-Report from an Interdisciplinary Workshop. Environmental Health Perspectives 115: 1654-1659, 2007.

Lee HA, Imran M, Monteiro-Riviere NA, Colvin VL, Yu WW, Riviere JE: Biodistribution of quantum dot nanoparticles in perfused skin: evidence of coating-dependency and periodicity in arterial extraction. Nano Letters 7:2865-2870, 2007.

Monteiro-Riviere NA, Orsiere T: Toxicological Impacts of Nanomaterials. In Environmental Nanotechnology: Applications and Impacts of Nanomaterials. (MR Wiesner and JY Bottero), McGraw-Hill New York, NY, Chapter 11, 395-444,2007.

Witzmann FA and Monteiro-Riviere NA: Effect of Carbon Nanotube Exposure on Keratinocyte Protein Expression. In Nanotoxicology: Characterization, Dosing, and Health Effects. (Eds. NA Monteiro-Riviere and CL Tran), Informa Healthcare, New York, NY, Chapter 13, 197-224, 2007.

Riviere JE and Tran CL. Pharmacokinetics of Nanomaterials. In Nanotoxicology: Characterization, Dosing, and Health Effects. (Eds. NA Monteiro-Riviere and CL Tran), Informa Healthcare, New York, NY, Chapter 9, 127-152, 2007.

Monteiro-Riviere NA, Inman AO, Ryman-Rasmussen JP. Dermal Effects of Nanomaterials: In Nanotoxicology: Characterization, Dosing, and Health Effects. (Eds. NA Monteiro-Riviere and CL Tran), Informa Healthcare, New York, NY, Chapter 19, 317-337, 2007.

Calabrese EJ, Riviere JE, Mattson MP: Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicology and Applied Pharmacology 222: 122-128, 2007.

Riviere, JE: Dermatotoxicology: Computational Risk Assessment. Computational Toxicology Risk Assessment for Pharmaceutical and Environmental Chemicals 677-692, 2007.

Xia XR, Baynes RE, Monteiro-Riviere NA, Riviere JE: An experimentally based approach for predicting skin permeability of chemicals and drugs using a membrane-coated fiber array. Toxicology and Applied Pharmacology 221: 320-328, 2007.

Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA: Variables Influencing Interactions of Untargeted Quantum Dot Nanoparticles with Skin Cells and Identification of Biochemical Modulators. Nano Letters 7(5): 1344-1348, 2007.

Zhang LW, Zeng L, Barron AR, Monteiro-Riviere NA: Biological Interactions of Functionalized Single-Wall Carbon Nanotubes in Human Epidermal Keratinocytes. International Journal of Toxicology 26:103-113, 2007.

Muhammad F, Riviere JE: Dermal toxicity. In Veterinary Toxicology, (Ed. RC Gupta),1st ed., Elsevier, New York, NY, Chapt. 16, pp. 263-276, 2007.

van der Merwe D, Buur JL, Riviere JE: Physiologically based pharmacokinetic modeling. In Veterinary Toxicology, (Ed. RC Gupta), 1st ed., Elsevier, New York, NY, Chapt. 3, pp. 42-50, 2007.

Walker GM, Monteiro-Riviere N A, Rouse J, O'Neill AT: A linear dilution microfluidic device for cytotoxicity assays. Lab Chip 7: 226-232, 2007.

KuKanich B, Huff D, Riviere JE, Papich MG: Naïve averaged, naïve pooled, and population pharmacokinetics of orally administered marbofloxacin in juvenile harbor seals. Journal of the American Veterinary Medical Association 230: 390-395, 2007.

Riviere JE, Brooks JD: Prediction of dermal absorption from complex chemical mixtures: incorporation of vehicle effects and interactions into a QSPR framework. SAR and QSAR in Environment Research 18: 31-44, 2007.

Wei W, Sethuraman A, Jin C, Monteiro-Riviere NA, Narayan RJ: Biological Properties of Carbon Nanotubes. Journal of Nanoscience and Nanotechnology 7:1-14,2007.

Rouse JG, Yang J, Ryman-Rasmussen, Barron AR, Monteiro-Riviere NA: Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin. Nano Letters 7: 155-160, 2007.

Leduc PR, Wong MS, Ferreira PM, Groff RE, Haslinger K, Koonce MP, Lee WY, Love JC, McCammon JA, Monteiro-Riviere NA, Rotello VM, Rubloff GW, Westervelt R, Yoda M: Towards an in vivo biologically inspired nanofactory. Nature Nanotechnology 2: 3-7, 2007.

Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA: Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes. Journal of Investigative Dermatology 127: 143-153, 2007.

Wei C, Lyubchencho YL, Ghandehari H, Hanes J, Stebe KL, Mao HQ, Haynie DT, Tomalia DA, Foldvari M, Monteiro-Riviere N, Simeonova P, Nie S, Mori H, Gilbert SP, Needham D.: New technology and clinical applications of nanomedicine: Highlights of the second annual meeting of the American Academy of Nanomedicine (Part1). Nanomedicine: Nanotechnology, Biology and Medicine 2: 253-263, 2006.

Monteiro-Riviere NA, Inman AO, Barlow BM, Baynes RE: Dermatotoxicity of cutting fluid mixtures: In vitro and in vivo studies. Cutaneous and Ocular Toxicology 25: 235-247, 2006.

Kong XQ, Shea D, Baynes RE, Riviere JE, Xia XR: Regression method of the hydrophobicity ruler approach for determining octanol/water partition coefficients of very hydrophobic compounds. Chemosphere 2006.

Rouse JG, Yang J, Barron AR, Monteiro-Riviere NA: Fullerene-based amino acid nanoparticle interactions with human epidermal keratinocytes. Toxicology in Vitro 20: 1313-1320, 2006.

Xia XR, Monteiro-Riviere NA, Riviere JE: Trace analysis of fullerenes in biological samples by simplified liquid-liquid extraction and high-performance liquid chromatography. Journal of Chromatography A 1129: 216-222, 2006.

Payne MA, Craigmill A, Riviere JE,Webb AI: Extralabel use of penicillin in food animals. Journal of the American Veterinary Medical Association 229: 1401-1403, 2006.

Willens S, Stoskopf MK, Baynes RE, Lewbart GA, Taylor SK, Kennedy-Stoskopf S: Percutaneous malathion absorption by anuran skin in flow-through diffusion cells. Environmental Toxicology and Pharmacology 22: 255-262, 2006.

Willens S, Stoskopf MK, Baynes RE, Lewbart GA, Taylor SK, Kennedy-Stoskopf S: Percutaneous malathion absorption in the harvested perfused anuran pelvic limb. Environmental Toxicology and Pharmacology 22: 263-267, 2006.

Witzmann FA and Monteiro-Riviere, NA: Multi-walled carbon nanotube exposure alters protein expression in human keratinocytes. Nanomedicine: Nanotechnology, Biology, and Medicine 2: 158-168, 2006.

Buur JL, Baynes RE, Smith G and Riviere JE: Pharmacokinetics of flunixin meglumine in swine after intravenous dosing. Journal of Veterinary Pharmacology and Therapeutics 29: 437-440, 2006.

van der Merwe, D and Riviere JE: Cluster analysis of the dermal permeability and stratum corneum/solvent partitioning of ten chemicals in twenty-four chemical mixtures in porcine skin. Skin Pharmacology and Physiology 19: 198-206, 2006.

Buur J, Baynes R, Smith G and Riviere J: Use of probabilistic modeling within a physiologically based pharmacokinetic model to predict sulfamethazine residue withdrawal times in edible tissues in swine. Antimicrobial Agents and Chemotherapy 50: 2344-2351, 2006.

Gehring R and Smith GW: An overview of factors affecting the disposition of intramammary preparations used to treat bovine mastitis. Journal of Veterinary Pharmacology and Therapeutics 29: 237-241, 2006.

Monteiro-Riviere NA, Inman A, Hedgepeth V, Mosteller B, Piedrahita J: Dermatological effects of chronic exposure to 7,12-dimethylbenz[a]anthracene (DMBA) or N-methyl-n-nitrosoguanidine (MNNG) in swine. Cutaneous and Ocular Toxicology 25: 103-119, 2006.

Monteiro-Riviere NA: The Integument. In Dellman's Textbook of Veterinary Histology (Eds. JA Eurell, BL Frappier, 6th Edition) Blackwell Publishing, Ames, Iowa. Chapter 16, pp.320-349, 2006.

Yang J-H, Lee C-H, Monteiro-Riviere NA, Riviere JE, Tsang C-L, Chou C-C: Toxicity of jet fuel aliphatic and aromatic hydrocarbon mixtures on human epidermal Keratinocytes: evaluation based on in vitro cytotoxicity and interleukin-8 release. Archives of Toxicology 80: 508-523, 2006.

Chou CC, Yang JH, Chen SD, Monteiro-Riviere NA, Li HN, Chen JJW: Expression profiling of human epidermal keratinocyte response following 1-minute JP-8 exposure. Journal of Cutaneous and Ocular Toxicology 25: 141-153, 2006.

Tournas JA, Lin FH, Burch JA, Selim MA, Monteiro-Riviere NA, Zielinski JE, Pinnell SR: Ubiquinone, idebenone and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid. Journal of Investigative Dermatology 126: 1185-1187, 2006.

Monteiro-Riviere NA, Ryman-Rasmussen JP: Toxicology of Nanomaterials. In Biological Concepts and Techniques in Toxicology, (Ed. JE Riviere), Taylor and Francis, Chapter 12, pp. 217-233, 2006.

Baynes RE, Buur JL: Chemical Risk Assessment. In Biological Concepts and Techniques in Toxicology, (Ed. JE Riviere), Taylor and Francis, Chapter 7, pp. 93-116, 2006.

Ryman-Rasmussen JP, Riviere JE, Monteiro-Riviere NA: Penetration of intact skin by quantum dots with diverse physicochemical properties. Toxicological Sciences 91: 159- 165, 2006.

Gehring R, Baynes RE, Riviere JE: Application of risk assessment and management principles to the extralabel use of drugs in food-producing animals. Journal of Veterinary Pharmacology and Therapeutics 29: 5-14, 2006.

Riviere JE: Dermal Absorption/Toxicity of Organophosphates and Carbamates. In Toxicology of Organophosphate and Carbamate Compounds, (Ed. RC Gupta), Elsevier Academic Press, Chapter 30, pp. 411-422, 2006.

Riviere JE: Chemical Mixtures. In Dermal Absorption Models in Toxicology and Pharmacology, (Ed. JE Riviere), CRC Press, Taylor and Francis Group, New York, NY. Chapter 14, pp. 283-304, 2006.

Baynes RE: Gulf War Syndrome: Risk Assessment Case Study. In Dermal Absorption Models in Toxicology and Pharmacology, (Ed. JE Riviere), CRC Press, Taylor and Francis Group, New York, NY. Chapter 9, pp.59 -176, 2006.

Xia XR, Baynes RE, Riviere JE: A Novel System Coefficient Approach for Systematic Assessment of Dermal Absorption from Chemical Mixtures. In Dermal Absorption Models in Toxicology and Pharmacology, (Ed. JE Riviere), CRC Press, Taylor and Francis Group, New York, NY. Chapter 5, p.71 88, 2006.

Muhammad F, Riviere JE: In Vivo Models. In Dermal Absorption Models in Toxicology and Pharmacology, (Ed. JE Riviere), CRC Press, Taylor and Francis Group, New York, NY. Chapter 4, pp.49-70, 2006.

Riviere JE: Perfused Skin Models. In Dermal Absorption Models in Toxicology and Pharmacology, (Ed. JE Riviere), CRC Press, Taylor and Francis Group, New York, NY. Chapter 3, pp. 29-48, 2006.

Monteiro-Riviere N: Structure and Function of the Skin. In Dermal Absorption Models in Toxicology and Pharmacology, (Ed. JE Riviere), CRC Press, Taylor and Francis Group, New York, NY. Chapter 1, pp 1-19, 2006.

Monteiro-Riviere NA, Inman AO: Challenges for assessing carbon nanomaterial toxicity to the skin. Carbon 44: 1070-1078, 2006.

Van der merwe D, Brooks JD, Gehring R, Baynes RE, Monteiro-Riviere NA, Riviere JE: A physiological-based pharmacokinetic model of organophosphate dermal absorption. Toxicological Sciences , 188-204, 2006.

Baynes RE, Brooks JD, Barlow BM, Riviere JE: NDELA and nickel modulation of triazine disposition in skin. Toxicology and Industrial Health, 197-205, 2005.

Lin FH, Lin JY, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinnell SR: Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology 125: 826-832, 2005.

Baynes RE, Yeatts JL, Brooks JD, Riviere JE: Pre-treatment effects of trichloroethylene on the dermal absorption of the biocide, triazine. Toxicology Letters 159: 252-260, 2005.

Monteiro-Riviere NA, Inman AO, Wang YY, Nemanich RJ: Surfactant effects on carbon nanotube interactions with human epidermal keratinocytes. Nanomedicine: Nanotechnology, Biology and Medicine 1: 293-299, 2005.

Monteiro-Riviere NA, Riviere JE: The Pig as a Model for Human Skin Research. In "Swine in Biomedical Research: Update on Animal Models". (Eds. M Swindle and GF Bouchard) Sinclair Research Center, p.17-22, 2005.

KuKanich B, Gehring R, Webb AI, Craigmill AL, Riviere JE: Effect of formulation and route of administration on tissue residues and withdrawal times. Journal of the American Veterinary Medical Association 227: 1574-1577, 2005.

Holsapple, MP, Farland WH, Landry TD, Monteiro-Riviere NA, Carter JM, Walker NJ, Thomas KV: Research Strategies for Safety Evaluation of Nanomaterials, Part II: Toxicological and safety evaluation of nanomaterials, current challenges and data needs. Toxicological Sciences 88: 12-17, 2005.

Buur JL, Baynes RE, Craigmill AL, Riviere JE: Development of a physiologic-based pharmacokinetic model for estimating sulfamethazine concentrations in swine and application to prediction of violative residues in edible tissues. American Journal of Veterinary Research 66: 1686-1693, 2005.

Witzmann FA, Monteiro-Riviere NA, Inman AO, Kimpel MA, Pedrick NM, Ringham HN, Riviere JE: Effect of JP-8 jet fuel exposure on protein expression in human keratinocyte cells in culture. Toxicology Letters 160: 8-21, 2005.

Oberdorster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman, K, Carter J, Karn B, Kreyling W, Lai D, Olin S, Monteiro-Riviere N, Warheit D, Yang H, and A Report from the ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group: Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Particle and Fibre Toxicology 2: 8: 1-35, 2005. [

Riviere JE, Brooks JD: Predicting skin permeability from complex chemical mixtures. Toxicology and Applied Pharmacology 208: 99-110, 2005.

Ferreira P, Groff R, Haslinger K, Koonce M, Le Duc P, Lee W, Love C, Mc Gammon A, Monteiro-Riviere N, Rotello V, Rubloff G, Westervelt R, Wong M, Yoda M. An in vivo nanofactory: the medicine of the future. National Academies on Designing Nanostructures at the Interface between Biomedical and Physical Systems. The National Academies Press, Washington, DC, pp. 53-60,2005

Xia XR, Baynes, RE, Monteiro-Riviere NA, Riviere JE: Membrane uptake kinetics of jet fuel aromatic hydrocarbons from aqueous solutions studied by a membrane-coated fiber technique. Toxicology Mechanisms and Methods 15: 307-316, 2005.

Gehring R, Haskell SR, Payne MA, Craigmill AL, Webb, AI, Riviere JE: Amino-glycoside residues in food of animal origin. Journal of the American Medical Association 227:63-66, 2005.

Smith GW, Gehring R, Craigmill AL, Webb AI, Riviere JE: Extralabel intramammary use of drugs in dairy cattle. Journal of the American Medical Association 226:1994-1996, 2005.

Buur JL,Baynes RE, Yeatts JL, Davidson G, DeFrancesco TC: Analysis of diltiazem in Lipoderm(r) transdermal gel using reversed-phase high-performance liquid chromatography applied to homogenization and stability studies. Journal of Pharmaceutical and Biomedical Analysis 38:60-65, 2005.

Muhammad F, Monteiro-Riviere NA, Baynes RE, Riviere JE: Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents. Journal of Toxicology and Environmental Health 68:719-737, 2005.

Haskell SR, Payne M, Webb A, Riviere JE, Craigmill AL: Antidotes in food animal practice. Journal of the American Veterinary Medical Association 226:884-887, 2005.

Muhammad, F, Monteiro-Riviere NA, Riviere JE: Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: Identification of tridecane and tetradecane as key constituents responsible for dermal irritation. Toxicologic Pathology 33:258-266, 2005.

Monteiro-Riviere NA, Nemanich RJ, Inman AO, Wang YY, Riviere JE: Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicology Letters 155:377-384, 2005.

Gehring R, van der Merwe D, Pierce A, Baynes R, Craigmill A, Riviere JE: Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle. American Journal of Veterinary Research 66:108-112, 2005.

Xia, XR, Baynes RE, Monteiro-Riviere NA, Riviere JE: Determination of the partition coefficients in a lipophilic membrane/water system by using a membrane-coated fiber technique. European Journal of Pharmaceutical Sciences 24:15-23, 2005.

Van der Merwe D, Riviere JE: Effect of vehicles and sodium lauryl sulphate on xenobiotic permeability and stratum corneum partitioning in porcine skin. Toxicology 206:325-335, 2005.

Van der Merwe D, Riviere JE: Comparative studies on the effects of water, ethanol and water/ethanol mixtures on chemical partitioning into porcine stratum corneum and silastic membrane. Toxicology in Vitro 19:69-77, 2005.

Martinez M, Papich MG, Riviere JE: Veterinary Application of in vitro dissolution data and the biopharmaceutics classification system. Pharmacopeial Forum 30:2295-2303, 2004.

Udomkusonsri P, Noga EJ, Monteiro-Riviere NA: Pathogenesis of acute ulceration response (AUR) in hybrid striped bass. Diseases of Aquatic Organisms 61:199-213, 2004.

Lin JY, Lin FH, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Pinnell SR: α -Lipoic acid is ineffective as a topical antioxidant for photoprotection of skin. Journal of Investigative Dermatology 123: 996-998, 2004.

Craigmill AL, Miller GR, Gehring R, Pierce AN, Riviere JE: Meta-analysis of pharmacokinetic data of veterinary drugs using the Food Animal Residue Avoidance Databank: oxytetracycline and procaine. Journal of Veterinary Pharmacology and Therapeutics 27:343-353, 2004.

Xia XR, Baynes RE, Monteiro-Riviere NA, Riviere JE: A compartment model for the membrane-coated fiber technique used for determining the absorption parameters of chemicals into lipophilic membranes. Pharmaceutical Research 21: 1345-1352, 2004.

Xia XR, Baynes RE, Monteiro-Riviere NA, Riviere JE: Characterization of polyacrylate membrane-coated fibers used in chemical absorption studies with programmed thermal treatment and FT-IR microscopy. Analytical Chemistry 76: 4245-4250, 2004.

Gehring R, Baynes RE, Wang J, Craigmill AL, Riviere JE: A web-based decision support system to estimate extended withdrawal intervals. Computers and Electronics in Agriculture 44:145-151, 2004.

Smith GW, Gehring R, Riviere JE, Yeatts JL, Baynes RE: Elimination kinetics of ceftiofur hydrochloride after intramammary administration in lactating dairy cows. Journal of the American Veterinary Medical Association 224: 1827-1830, 2004.

Muhammad F, Brooks J, Riviere JE: Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems. Toxicology Letters 150: 351-365, 2004.

Baynes RE: In vitro dermal disposition of abamectin (avermectin B1) in livestock. Research in Veterinary Science 76: 235-242, 2004.

Muhammad F, Baynes RE, Monteiro-Riviere NA, Xia XR, Riviere JE: Dose related absorption of JP-8 jet fuel hydrocarbons through porcine skin with quantitative structure permeability relationship analysis. Toxicology Mechanisms and Methods 14: 159-166, 2004.

Gehring R, Baynes RE, Craigmill AL, Riviere JE: Feasibility of using half-life multipliers to estimate extended withdrawal intervals following the extralabel use of drugs in food-producing animals. Journal of Food Protection 67: 555-560, 2004.

Monteiro-Riviere NA, Inman A, Riviere JE: Skin toxicity of jet fuels: ultrastructural studies and the effects of substance P. Toxicology and Applied Pharmacology 195:339-347, 2004.

Baynes RE: Human Health Risk Assessment. In A Textbook of Modern Toxicology, 3rd Edition (Ed. E. Hodgson), John Wiley and Sons, Inc., Hoboken, NJ. Chapter 24, pp. 423-438, 2004.

Baynes RE: Absorption and Distribution of Toxicants. In A Textbook of Modern Toxicology, 3rd Edition (Ed. E. Hodgson), John Wiley and Sons, Inc., Hoboken, NJ. Chapter 6, pp. 77-110, 2004.

Riviere JE: Isolated Perfused Porcine Skin Flap. In Dermatotoxicology, 6th Edition (Eds. H. Zhai and HI Maibach), CRC Press, Washington, DC. Chapter 31, pp. 563-588, 2004.

Riviere JE: Percutaneous Absorption of Complex Chemical Mixtures. In Dermatotoxicology, 6th Edition (Eds. H. Zhai, and HI Maibach), CRC Press, Washington, DC. Chapter 3, pp. 29-41, 2004.

Monteiro-Riviere NA: Anatomical Factors Affecting Barrier Function. In Dermatotoxicology, 6th Edition (Eds. H. Zhai, and HI Maibach), CRC Press, Washington, DC, Chapter 4, pp.42-70, 2004.

Webb AI, Baynes RE, Craigmill AL, Riviere JE, Haskell SR: Drugs approved for small ruminants. Journal of the Veterinary Medical Association 224: 520-523, 2004.

Baynes RE, Riviere JE: Mixture additives inhibit the dermal permeation of the fatty acid, ricinoleic acid. Toxicology Letters 147: 15-26, 2004.

Wang J, Gehring R, Baynes RE, Webb AI, Whitford C, Payne MA, Fitzgerald K, Craigmill AL, Riviere JE: Evaluation of the advisory services provided by the Food Animal Residue Avoidance Databank. Journal of the Veterinary Medical Association 223: 1596-1598, 2003.

Xia X-R, Baynes RE, Monteiro-Riviere NA, Leidy RB, Shea D, Riviere JE: A novel in vitro technique for studying percutaneous permeation with a membrane-coated fiber and gas chromatography/mass spectrometry: Part I. Performances of the technique and determination of the permeation rates and partition coefficients of chemical mixtures. Pharmaceutical Research 20: 275-282, 2003.

Baynes RE, Barlow BM, Riviere JE: Dermal disposition of triazine in cutting fluid mixtures. Journal of Toxicology-Cutaneous and Ocular Toxicology 22:215-229, 2003.

Lin JY, Selim MA, Shea CR, Grichnik JM, Omar MM, Monteiro-Riviere NA, Pinnell SR: UV photoprotection by combination topical antioxidants vitamin C and vitamin E. Journal of the American Academy of Dermatology 48: 866-874, 2003.

Chou CC, Riviere JR, Monteiro-Riviere NA: The cytotoxicity of jet fuel aromatic hydrocarbons and dose-related interleukin-8 release from human epidermal keratinocytes. Archives of Toxicology 77: 384-391, 2003.

Inman AO, Still KR, Jederberg WW, Carpenter RL, Riviere JE, Brooks JD, Monteiro-Riviere NA: Percutaneous absorption of 2,6-di-tert-butyl-4-nitrophenol (DBNP) in isolated perfused porcine skin. Toxicology in Vitro 17: 289-292, 2003.

Riviere JE, Baynes RE, Brooks JD, Yeatts JL, Monteiro-Riviere NA: Percutaneous absorption of topical diethyl-m-toluamide (DEET): Effects of exposure variables and co-administered toxicants. Journal of Toxicology and Environmental Health, Part A 66:133-151, 2003.

Monteiro-Riviere NA, Van Miller JP, Simon GS, Joiner RL, Brooks J, Riviere JE: In Vitro percutaneous absorption of nonylphenol (NP) and nonylphenol ethoxylates (NPE-4 and NPE-9 in isolated perfused skin. Journal of Toxicology-Cutaneous and Ocular Toxicology 22: 1-11, 2003.

Monteiro-Riviere NA, Baynes RE, Riviere JE: Pyridostigmine bromide modulates topical irritant-induced cytokine release from human epidermal keratinocytes and isolated perfused porcine skin. Toxicology 183:15-28, 2003.

Martinez-Jimenez T, Baynes RE, Craigmill A, Riviere JE: Extrapolated withdrawal-interval estimator (EWE) algorithm: A quantitative approach to establishing extralabel withdrawal times. Regulatory Toxicology and Pharmacology 36: 131-137, 2002.

Baynes RE, Brooks JD, Barlow BM, Riviere JE: Physicochemical determinants of linear alkylbenzene sulfonate (LAS) disposition in skin exposed to aqueous cutting fluid mixtures. Toxicology and Industrial Health 18:237-248, 2002.

Baynes RE, Brooks JD, Mumtaz M, Riviere JE: Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport. Toxicological Sciences 69: 295-305, 2002.

Baynes RE, Yeatts JL, Riviere JE: Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phased high-performance liquid chromatography. Journal of Chromatography B 780: 45-52, 2002.

Riviere JE, Monteiro-Riviere NA, Baynes RE: Gulf War related exposure factors influencing topical absorption of C14 - permethrin. Toxicology Letters 135: 61-71, 2002.

Chou CC, Riviere JE, Monteiro-Riviere NA: Differential relationship between carbon chain-length of jet fuel aliphatic hydrocarbons and their ability to induce cytotoxicity versus interleukin-8 release in human epidermal keratinocytes. Toxicological Sciences 69: 226-233, 2002.

Baynes RE, Monteiro-Riviere NA, Riviere JE: Pyridostigmine bromide modulates the dermal disposition of [14C] permethrin. Toxicology and Applied Pharmacology 181: 164-173, 2002.

Martín-Jiménez T, Riviere, JE: Mixed-effects modeling of the interspecies pharmacokinetic scaling of oxytetracycline. Journal of Pharmaceutical Sciences91: 331-341, 2002.

Rhyne BN, Pirone JR, Riviere JE, Monteiro-Riviere NA: The use of enzyme histochemistry in detecting cutaneous toxicity of three topically applied jet fuel mixtures. Toxicology Mechanisms and Methods 12:17-34, 2002.

Monteiro-Riviere NA, Inman AO, Jackson H, Dunn B, Dimond S. Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin. Toxicology and Industrial Health 17: 95-104, 2001.

Qiao GL, Riviere JE: Enhanced systemic tissue distribution after dermal versus intravenous 3,3', 4,4' - tetrachlorobiphenyl exposure. Limited utility of radiolabel blood area under the curve and excretion data in dermal absorption calculations and tissue exposure assessment. Toxicology and Applied Pharmacology 177: 26-37, 2001.

Inman AO, Olivry T, Dunston, SM, Gatto H and Monteiro-Riviere NA: Electron microscopic observations of stratum corneum intercellular lipids in normal and atopic dogs. Veterinary Pathology 38:720-723, 2001.

Monteiro-Riviere NA, Inman AO, Riviere JE: The effects of short-term high dose and low dose dermal exposure to Jet A, JP-8, and JP-8+100 jet fuels. Journal Applied Toxicology 21: 485-494, 2001.

Martin TM, Riviere JE: Mixed effects modeling of the disposition of gentamicin across domestic animal species. Journal of Veterinary Pharmacology and Therapeutics24: 321-332, 2001.

Allen DA, Riviere JE, Monteiro-Riviere NA: Analysis of interleukin-8 release from normal human epidermal keratinocytes exposed to aliphatic hydrocarbons: delivery of hydrocarbons to cell cultures via complexation with a-cyclodextrin. Toxicology In Vitro 15: 663-669, 2001.

Riviere JE, Qiao G, Baynes RE, Brooks JD, Mumtaz M: Mixture component effects on the in vitro dermal absorption of pentachlorophenol. Archives of Toxicology 75: 329-334, 2001.

Baynes RE: Isolated Perfused Porcine Skin Flap. Current Protocols in Toxicology, 1, 5.4.1-5.4.9, 2001.

Baynes RE: Porcine Skin Flow-through Diffusion Cell System. Current Protocols in Toxicology, 1, 5.5.1-5.5.8, 2001.

Baynes RE, Riviere JE: Pesticide Disposition: Dermal Absorption. Handbook of Pesticide Toxicology, Principles, 515-526, 2001.

Baynes RE, Brooks JD, Budsaba K, Smith CE, Riviere JE: Mixture Effects of JP-8 additives on the dermal disposition of jet fuel components. Toxicology and Applied Pharmacology 175, 269-281, 2001.

Riviere J, Papich M: Potential and problems of developing transdermal patches for veterinary applications. Advanced Drug Delivery Reviews 50: 175-203, 2001.

Allen DG, Riviere JE, Monteiro-Riviere NA: Cytokine induction as a measure of cutaneous toxicity in primary and immortalized porcine keratinocytes exposed to jet fuels, and their relationship to normal human epidermal keratinocytes. Toxicology Letters 119:209-217, 2001.

Monteiro-Riviere NA, Inman AO, Mak V, Wertz P, Riviere JE: Effect of selective lipid extraction from different body regions on epidermal barrier function. Pharmaceutical Research 18:992-998, 2001.

Pinnell SR, Yang H, Omar M, Monteiro-Riviere NA, Debuys HV, Walker LC, Wang Y, Levine M: Topical L-ascorbic acid: percutaneous absorption studies. Dermatological Surgery 27: 137-142, 2001.

Riviere JE, Smith CE, Budsaba K, Brooks JD, Olajos EJ, Salem H, Monteiro-Riviere NA: Use of methyl salicylate as a simulant to predict the percutaneous absorption of sulfur mustard. Journal Applied Toxicology 21: 91-99, 2001.

Monteiro-Riviere NA: Dermatotoxicology. An Introduction to Biochemical Toxicology, (Ed. E. Hodgson), John Wiley and Sons, NY. Chapt. 21, 509-537, 2001.

Argenzio RA and Monteiro-Riviere NA: The Excretory System. In The Biology of the Domestic Pig, (Eds. WG Pond and HJ Mersmann), Cornell University Press, Ithaca, NY. Chapt. 13, 585-624, 2001.

Monteiro-Riviere NA: Integument. In The Biology of the Domestic Pig, (Eds. W G Pond and HJ Mersmann), Cornell University Press, Ithaca, NY. Chapt. 14, 625-652, 2001.

Qiao G, Riviere JE: Dermal absorption and tissue disposition of 3,3',4,4'-tetrachlorobiphenyl (TCB) in an ex-vivo pig model: Assessing the impact of dermal exposure variables. International Journal of Occupational and Environmental Health 6: 127-137, 2000.

Baynes R, Brooks J, Riviere J: Membrane transport of napthalene and dodecane in jet fuel mixtures. Toxicology and Industrial Health 16: 225-238 2000.

Riviere JE, Brooks J, Qiao G: Methods of assessing the percutaneous absorption of volatile chemicals in isolated perfused skin: studies with chloropentafluorobenzene and dichlorobenzene. Toxicology Methods 10:265-281, 2000.

Monteiro-Riviere NA, Allen DA, Riviere JE: Use of the pig as a model to assess cutaneous toxicity and inflammation of jet fuels. Journal of Veterinary Pharmacology and Therapeutics 23: (Suppl.1 CD) F:12, 2000.

Budsaba K, Smith CE, Riviere JE: Compass plots: a combination of star plot and analysis of means to visualize significant interactions in complex toxicology studies. Toxicology Methods 10:313-332, 2000.

Baynes R, Craigmill A, Riviere JR: Residue avoidance after topical application of veterinary drugs and parasiticides. Journal of American Veterinary Medical Association 210:1288-1289, 2000.

Baynes R, Payne M, Martin-Jimenez T, Abdullah A-R, Anderson K, Webb A, Craigmill A, Riviere JE: Extralabel use of ivermectin and moxidectin in food. Journal of American Veterinary Medical Association 217:668-671, 2000.

Allen DG, Riviere JE, Monteiro-Riviere NA: Identification of early biomarkers of inflammation produced by keratinocytes exposed to jet fuels Jet A, JP-8, and JP-8 (100) Journal of Biochemical and Molecular Toxicology 14:231-237, 2000.

Monteiro-Riviere NA, Inman AO: Characterization of sulfur mustard-induced toxicity by enzyme histochemistry in porcine skin. Toxicology Methods 10:127-142, 2000.

Qiao GL, Chang SK, Brooks JD, Riviere JE: Dermatotoxicokinetic modeling of p-nitrophenol and its conjugation metabolite in swine following topical and intravenous administration. Toxicological Sciences 54:284-294, 2000.

Monteiro-Riviere NA, Van Miller JP, Simon G, Joiner RL, Brooks JD, Riviere JE: Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin. Toxicology and Industrial Health 16:49-57, 2000.

Baynes RE, Lyman R, Anderson KL, Brownie CF: A Preliminary Survey of Antibiotic Residues and Viable Bacteria in Milk from Three Caribbean Basin Countries. Journal of Food Protection 62: 177-180, 1999.

Riviere JE, Brooks JD, Monteiro-Riviere NA: Dermal absorption and distribution of topically dosed jet fuels JET-A, JP-8, and JP-8 (100). Toxicology and Applied Pharmacology 160:60-75, 1999.

Baynes RE, Martin-Jimenez T, Craigmill AL, Riviere JE: Estimating provisional acceptable residues for extralabel drug use in livestock. Regulatory Toxicology and Pharmacology 29: 287-299, 1999.

Monteiro-Riviere NA, Inman AO, Babin MC, Casillas RP: Immunohistochemical characterization of the basement membrane epitopes in bis(2-chloroethyl) sulfide-induced toxicity in mouse ear skin. Journal of Applied Toxicology 19:313-328, 1999.

Allen DA, Monteiro-Riviere NA: Alteration of cytokeratin expression following transdermal lidocaine hydrochloride iontophoresis. Pharmaceutical Research 16:1487-1490, 1999.

Monteiro-Riviere NA and Riviere JE: Skin toxicology. Toxicology, (Eds. H Marquardt, S Schäfer, R McClellan, F Welsch), Academic Press, San Diego, CA, Chapt. 18, 439-457, 1999.

Martin-Jimenez T, Papich MG, Riviere JE: Population pharmacokinetics of gentamicin in horses. American Journal of Veterinary Research 59:1589-1598, 1998.

Monteiro-Riviere NA: Integument. Textbook of Veterinary Histology. (Eds.H.D. Dellmann and J. Eurell) Williams and Wilkins, Baltimore, MD, Chapter 16, pp 303-332, 1998.

Riviere JE, Webb AI, Craigmill AL. Primer on estimating withdrawal times after extralabel drug use. Journal of American Veterinary Medical Association 213:966-968, 1998.

Wester RC, Melendres J, Sedik L, Maibach H, Riviere JE: Percutaneous absorption of salicylic acid, theophylline, 2,4-dimethylamine, diethyl hexyl phthalic acid, and p-aminobenzoic acid in the isolated perfused porcine skin flap compared to man in vivo. Toxicology and Applied Pharmacology 151: 159-165, 1998.

Riviere JE, Baynes RE: Dermal Absorption and Toxicity Assessment. Drugs and The Pharmaceutical Sciences. (Eds. MS Roberts and KA Walters) Marcel Dekker, Inc. NY, NY. Vol.91:Chapter 24, 625-645, 1998.

Martin-Jimenez M, Riviere JE: Population pharmacokinetics in veterinary medicine: Potential use for therapeutic drug monitoring and prediction of tissue residues. Journal of Veterinary Pharmacology Therapeutics 21:167-189, 1998.

Olivry T, Fine JD, Dunston SM, Chasse D, Tenorio AP, Monteiro-Riviere NA, Chen M, Woodley DT: Canine epidermolysis bullosa acquisita: circulating autoantibodies target the aminoterminal noncollagenous (NC1) domain of collagen VII in anchoring fibrils. Veterinary Dermatology 9:19-31, 1998.

Zhang Z, Fine JD, Monteiro-Riviere NA: Uncein may be a potential target for sulfur mustard alkylation. Toxicology Methods 8:27-36, 1998.

Baynes RE, Riviere JE: Influence of inert ingredients in pesticide formulations on dermal absorption of carbaryl. American Journal of Veterinary Research 59:168-175, 1998.

Riviere JE. Why our food is safer through science. Research Triangle Publishing, Inc., Fuquay-Varina, NC, 1-257. 1997.

Baynes RE, Monteiro-Riviere NA, Qiao GL, Riviere JE: Cutaneous toxicity of the benzidine dye direct red 28 applied as mechanistically-defined chemical mixtures (MDCM) in perfused porcine skin. Toxicology Letters 93:159-169, 1997.

Riviere JE, Martin-Jimenez T, Sundlof SF, Craigmill AJ: Interspecies allometric analysis of the comparative pharmacokinetics of 44 drugs across veterinary and laboratory animal species. Journal of Veterinary Pharmacology and Therapeutics 20: 453-463, 1997.

Qiao GL, Brooks JD, Riviere JE: Pentachlorophenol dermal absorption and disposition from soil in swine: Effects of occlusion and skin microorganism inhibition. Toxicology and Applied Pharmacology 147: 234-246, 1997.

Swanson WF, Wolfe BA, Brown JL, Martin-Jimenez T, Riviere JE, Roth TL, Wildt DE: Pharmacokinetics and ovarian-stimulatory effects of equine and human chorionic gonadotropins administered singly and in combination in the domestic cat. Biology of Reproduction 57: 295-302, 1997.

Zhang Z, Monteiro-Riviere NA: Comparison of integrins in human skin, pig skin, and perfused skin: an in vitro skin toxicology model. Journal of Applied Toxicology 17: 247-253, 1997.

Riviere JE, Monteiro-Riviere NA, Inman AO: The effect of altered media flow and glucose concentration on sulfur mustard toxicity in the isolated perfused porcine skin flap. In Vitro Toxicology 10: 169-181, 1997.

Riviere JE, Heit MC: Electrically-assisted transdermal drug delivery. Pharmaceutical Research 14: 687-697, 1997.

Riviere JE: Basic principles and techniques of pharmacokinetic modeling. Journal of Zoo and Wildlife Medicine 28: 3-19, 1997.

Baynes RE, Halling KB, Riviere JE: The influence of diethyl-m-toluamide (DEET) on the percutaneous absorption of permethrin and carbaryl. Toxicology and Applied Pharmacology 144: 332-339, 1997.

Potts RO, Bommannan D, Wong O, Tamada JA, Riviere JE Monteiro-Riviere NA : Transdermal Peptide Delivery Using Electroporation. Protein Delivery: Physical Systems, (Eds. Sanders and Hendren), Plenum Press, New York, NY, Chapter 8, 213-237, 1997.

Monteiro-Riviere NA, Inman AO, Snider TH, Blank JA, Hobson DW: Comparison of an in vitro skin model to normal human skin for dermatological research. Microscopy Research and Technique 37:172-179, 1997.

Monteiro-Riviere NA, Inman AO : Ultrastructural characterization of sulfur mustard-induced vesication in isolated perfused porcine skin. Microscopy Research and Technique 37:229-241, 1997.

Monteiro-Riviere NA, Zhang Z, Riviere JE: Integrated biochemical and molecular mechanisms of sulfur mustard vesication in skin: Vascular and basement membrane targets. In Proceedings of the 1996 Medical Defense Bioscience Review, 977-986, 1996.

Vaden SL, Page RL, Riviere JE: An in vitro validation of the isolated perfused tumor and skin flap preparation as a model of cisplatin delivery to tumors. Journal of Pharmacological and Toxicological Methods 35: 173-177, 1996

Monteiro-Riviere NA, Riviere JE: The pig as a model for cutaneous pharmacology and toxicology research. Swine In Biomedical Research, (Eds. ME Tumbleson and LB Schook), Plenum Publishing Corporation, New York, NY, Vol.II, Chapt. 38, 425-458, 1996.

Murtaugh MP, Monteiro-Riviere NA, Panepinto L: Swine Research Breeds, Methods, and Biomedical Models. Swine In Biomedical Research, (Eds. ME Tumbleson and LB Schook), Plenum Publishing Corporation, New York, NY, Vol. II, Chapt. 37, 423-424, 1996.

Monteiro-Riviere NA: Anatomical Factors Affecting Percutaneous Absorption. In Dermatotoxicology, 5th Edition (Eds. Marzulli FN and HI Maibach), Taylor and Francis, Washington, DC, pp.3-17, 1996.

Baynes RE, Brownie C, Freeman H, and Riviere JE: In vitro percutaneous absorption of benzidine in complex mechanistically defined chemical mixtures. Toxicology and Applied Pharmacology 141: 497-506, 1996.

Williams PL, Thompson D, Qiao GL, Monteiro-Riviere NA, and Riviere JE: The use of mechanistically defined chemical mixtures (MDCM) to assess mixture component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals. II. Development of a general dermatopharmacokinetic model for use in risk assessment. Toxicology and Applied Pharmacology 141: 487- 496, 1996.

Qiao GL, Brooks JD, Baynes RE, Monteiro-Riviere NA, Williams PL, and Riviere JE: The use of mechanistically defined chemical mixtures (MDCM) to assess component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals. I. Studies with parathion mixtures in isolated perfused porcine skin. Toxicology and Applied Pharmacology 141: 473-486, 1996.

Riviere: Isolated Perfused Porcine Skin Flap Systems: Models For Assessing Drug Absorption and Metabolism (Eds. Borchardt RT, Smith PL, and Wilson G). Plenum Press, New York, Chapt.21, 387-407, 1996.

Brooks JD, Riviere JE: Quatitative percutaneous absorption and cutaneous distribution of binary mixtures of phenol and para-nitrophenol in isolated perfused porcine skin. Fundamental and Applied Toxicology, 32: 233-243, 1996.

Riviere JE, Brooks JD, Williams PL, McGown E, Francoeur ML: Cutaneous metabolism of isosorbide dinitrate after transdermal administration in isolated perfused porcine skin. International Journal of Pharmaceutics, 127: 213-217, 1996.

Riviere JE: Isolated perfused porcine skin flap: Dermatotoxicology, 5th Ed. (Eds. Marzulli FN and Maibach HI) Taylor and Francis, Washington, DC, Chapter 27, 337-351, 1996. (date not certain)

Riviere JE, Vaden S: Drug therapy during renal disease and renal failure. In Osborne CA, Finco DR (Eds). Canine and Feline Nephrology and Urology. pp. 555-572, 1995.

Heit M, Riviere JE: Antifungal therapy; ketoconazole and other azole derivatives. Compendium Continuing Education Practice Veterinary. pp. 21-29, 1995.

Riviere JE, Monteiro-Riviere NA, Rogers RA, Bommannan D, Tamada JA, Potts RO: Pulsatile transdermal delivery of LHRH using electroporation: drug delivery and skin toxicology. Journal of Controlled Release 36: 229-233, 1995.

Riviere JE, Brooks JD, Williams PL, Monteiro-Riviere NA: Toxicokinetics of topical sulfur mustard penetration, disposition, and vascular toxicity in isolated perfused porcine skin. Toxicology and Applied Pharmacology 135: 25-34, 1995.

Riviere JE, Spoo JW: Chemical residues in tissue of food animals. In Adams HR. (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press. pp. 1148-1158, 1995.

Riviere JE, Spoo JW: Dermatopharmacology: Drugs acting locally on the skin. In Adams HR. (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press. pp. 1050-1090, 1995.

Heit MC, Riviere JE: Antifungal and antiviral drugs. Adams HR. (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press. pp. 855-884, 1995.

Spoo JW, Riviere JE: Chloramphenicol, macrolides, lincosamides, fluoroquinolones, and miscellaneous antibiotics. Adams HR (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press. pp. 820-854, 1995.

Riviere JE, Spoo JW: Aminoglycosides antibiotics. Adams HR. (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press pp. 797-819, 1995.

Riviere JE, Spoo JW: Tetracycline antibiotics. Adams HR (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press. pp. 784-796, 1995.

Vaden SL, Riviere JE: Penicillins and related b-lactam antibiotics. Adams HR (Eds). Veterinary Pharmacology and Therapeutics. Iowa State University Press. pp. 774-783, 1995.

Spoo JW, Riviere JE: Sulfonamides. In Adams HR (Eds). Veterinary Pharmacology and Therapeutics: Iowa State University Press. Pp. 753-773, 1995.

Heit, MC, Riviere JE: Antiseptics and disinfectants. In Adams HR (Eds) Veterinary

Pharmacology and Therapeutics: Iowa State University Press. pp.741-752, 1995.

Martinez, MN, Riviere JE, Koritz GD: Review of the first interactive workshop on professional flexible labeling. Journal of the American Veterinary Medical Association, 207:865-914, 1995.

Zhang Z, Peters BP, Monteiro-Riviere NA: Assessment of sulfur mustard interaction with basement membrane components. Cell Biology and Toxicology 11:89-101,1995.

Monteiro-Riviere NA, Inman AO: Indirect immunohistochemistry and immunoelectron

microscopy distribution of eight epidermal-dermal junction epitopes in the pig and in

isolated perfused skin treated with bis(2-chloroethyl)sulfide. Toxicologic Pathology

23:313-325, 1995.

Gordon CJ, Gray LE Jr., Monteiro-Riviere NA, Miller DB: Temperature regulation and metabolism in rates exposed perinatally to dioxin: Permanent change in regulated body temperature? Toxicology and Applied Pharmacology 133:172-176, 1995.

Chang SK, Brooks JD, Monteiro-Riviere NA, Riviere JE: Enhancing or blocking effect of fenvalerate on the subsequent percutaneous absorption of pesticides in vitro. Pesticide Biochemistry and Physiology 51:214-219, 1995.

Zhang Z, Riviere JE, Monteiro-Riviere NA: Topical sulfur mustard induces changes in

prostaglandins and interleukin-1a in isolated perfused porcine skin. In Vitro Toxicology

8:149-157, 1995.

Page RL, Lee J, Riviere JE, Dodge RK, Thrall DE, Dewhirst MW: Absence of whole body hyperthermia effect on cisplatin distribution in spontaneous canine tumors. Internation Journal of Radiation Oncology Biological Physiology 32:1097-1102, 1995.

Qiao GL, Riviere JE: Significant effects of application site and occlusion on the pharmacokinetics of cutaneous penetration and biotransformation of parathion in vivo in swine. Journal of Pharmaceutical Sciences 84:425-432, 1995.

Williams PL, Riviere JE: A biophysically based dermatopharmacokinetic compartment model for quantifying percutaneous penetration and absorption of topically applied agents. I. Theory. Journal of Pharmaceutical Sciences 84:599-608, 1995.

Riviere JE, Monteiro-Riviere NA, Williams PL: Isolated perfused porcine skin flap as an in vitro model for predicting transdermal pharmacokinetics. Eur. J. Pharm Biopharm 41:152-162, 1995.

Francoeur ML, Monteiro-Riviere NA, Riviere JE: Piroxicam: Evidence for local delivery following topical application. Eur. J. Pharm Biopharm 41:175-183, 1995.

Zhang, Z., Riviere, J.E., Monteiro-Riviere, N.A.: Evaluation of protective effects of sodium thiosulfate, cysteine, niacinamide and indomethacin on sulfur mustard-treated isolated perfused porcine skin. Chemico-Biological Interactions 96:249-262, 1995.

Qiao, G.L., Riviere, J.E.: Significant effects of application site and occlusion on the pharmacokinetics of cutaneous penetration and biotransformation of parathion in vivo in swine. Journal of Pharmaceutical Sciences 84:425-432, 1995.

Spoo, JW, Monteiro-Riviere, NA, Riviere, JE: Detection of sulfur mustard bus (2-chloroethyl) sulfide and metabolites after topical application in the isolated perfused porcine skin flap. Life Science 56:1385-1394 1995.

Monteiro-Riviere NA, Inman, AO, Riviere JE: Development and characterization of a novel skin model for phototoxicology. Photodermatology, Photoimmunology and Photomedicine 10:235-243, 1994.

Rogers RA, Riviere JE: Pharmacologic modulation of the cutaneous vasculature in the isolated perfused porcine skin flap (IPPSF). Journal of Pharmaceutical Science 83(12):1682-1689 1994.

Chang SK, Brownie C, Riviere JE: Percutaneous absorption of topical parathion through porcine skin: In vitro studies on the effect of environmental perturbations. Journal of Veterinary Pharmacology Therapeutics 17:434-439, 1994.

Chang SK, Williams PL, Dauterman WC, Riviere JE: Percutaneous absorption, dermatopharmacokinetics, and related biotransformation studies of carbaryl, lindane, malathion, and parathion in isolated perfused porcine skin. Toxicology 91:269-280, 1994.

Williams PL, Riviere JE: A "full-space" method for predicting in vivo transdermal plasma drug profiles reflecting both cutaneous and systemic variability. Journal of Pharmaceutical Science 83:1062-1064, 1994.

Riviere JE: Influence of compounding on bioavailability. Journal of the American Veterinary Medical Association, 205:226-231, 1994.

Heit MC, Monteiro-Riviere NA, Jayes, FL, Riviere JE: Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): Effect of repeated administration. Pharmaceutical Research 11(7) 1000-1003, 1994.

Vaden SL, Page RL, Williams PL, Riviere JE: Effect of hyperthermia on cisplatin and carboplatin disposition in the isolated perfused tumor and skin flap. Int. Journal Hyperthermia 10:563-572, 1994.

Martinez MN, Riviere JE: Review of the 1993 veterinary drug bioequilvalence workshop. Journal of Veterinary Pharmacology Therapeutics 17:85-119, 1994.

Qiao GL, Williams PL, Riviere JE: Percutaneous absorption, biotransformation, and systemic disposition of parathion in vivo in swine. I. Comprehensive pharmacokinetic model. Drug Metabolism and Disposition, 22:459-471, 1994.

Williams PL, Brooks JD, Inman AO, Monteiro-Riviere NA, Riviere JE: Determination of physicochemical properties of phenol, p-nitrophenol, acetone and ethanol relevant to quantitating their percutaneous absorption in porcine skin. Research Communications in Chemical Pathology and Pharmacology, 83:61-75, 1994.

Heit MC, McFarland A, Bock R, Riviere JE: Isoelectric focusing and capillary zone electrophoretic studies using luteinizing hormone releasing hormone (LHRH) and its analogues. Journal of Pharmaceutical Science, 83:654-656, 1994.

Chang SK, Williams PL, Riviere JE: Percutaneous absorption of carbaryl, lindane, malathion and parathion in isolated perfused porcine skin.

King, JR, Peters, B, Monteiro-Riviere NA: Laminin in the cutaneous basement membrane as a potential target in lewisite vesication. Toxicology and Applied Pharmacology, 126:164-173, 1994.

Monteiro-Riviere NA, Inman AO, Riviere JE: Identification of pathway of electrically assisted transdermal drug delivery: light and ultrastructural studies using mercuric chloride in pigs. Pharmaceutical Research, 11:251-256, 1994.

Chang SK, Dauterman WC, Riviere JE: Percutaneous absorption of parathion and its metabolites paraoxon and p-nitrophenol administered alone or in combination: in vitro flow through diffusion cell system. Pest. Biochem. Physiol., 48:56-62, 1994.

Monteiro-Riviere NA, Stinson AL, Calhoun HL: Integument: Textbook of Veterinary Histology. Ed. Dellmann Lea & Febiger , Philadelphia Chapter 16 pp 285-312, 1993.

Monteiro-Riviere NA, Inman AO, Spoo JW, Rogers RA, Riviere JE: Studies on the pathogenesis of bis(2-chloroethyl) sulfide (HD) induced vesication in porcine skin. Proceedings of the 1993 Medical Defense Bioscience Review. pp. 31-40, 1993.

Riviere JE, Monteiro-Riviere NA, Williams PL: Isolated perfused porcine skin flap as an In Vitro model for predicting transdermal pharmacokinetics. Flynn GL and Gonsalez M (Eds.) Pharmacokinetics and Pharmacodynamics of Drugs Delivered through the Skin, American Chemical Society, 1993.

Monteiro-Riviere NA, Inman AO, Riviere JE, McNeill SC, Francoeur ML: Topical penetration of piroxicam is dependent on the distribution of the local cutaneous vasculature. Pharmaceutical Research, 10:1326-1331, 1993.

Qiao G, Chang SK, Riviere JE: Effects of anatomical site and occlusion on the percutaneous absorption and residue pattern of 2,6-[ring-14C] parathion in vivo in pigs. Toxicology and Applied Pharmacology, 122:131-138, 1993.

DeWosken RS, Page RL, Riviere JE: Kidney trace metal response to combined cisplatin (CDDP) and hyperthermia. Int. Journal of Hyperthermia, 9:529-537, 1993.

Riviere JE, Monteiro-Riviere NA: Skin: porcine skin flaps, Tyson CA, Frazier JM (Eds.): Methods in Toxicology, Vol 1, New York, Academic Press. Chapter 45, pp. 515-524, 1993.

Riviere JE: Use of antimicrobial agents in the presence of renal impairment. Baggot JD (Ed.): Antimicrobial Therapy in Veterinary Medicine, Ames, Iowa State University Press.

Riviere JE: Grafted skin and skin flaps. Shah VP and Maibach HI (Eds). Cutaneous Bioavailability, Bioequivalence and Penetration, Plenum Press, New York.

Vaden SL, Williams PL, Page RL, Riviere JE: Effect of tumor presence on cisplatin and carboplatin disposition in the isolated perfused tumor and skin flap. Cancer Chemother. Pharmacol., 32:31-38, 1993.

Williams PL, Riviere JE: Model describing transdermal iontophoretic delivery of lidocaine incorporating consideration of cutaneous microvascular state. Journal of Pharmaceutical Science, 82:1080-1084, 1993.

Heit M, Williams P, Jayes FL, Chang SK, Riviere J: Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with luteinizing hormone releasing hormone (LHRH). Journal of Pharmaceutical Science, 82:240-243, 1993.

Chang SK, Riviere JE: Effect of humidity and occlusion on the percutaneous absorption of parathion in vitro. Pharmaceutical Research, 10:152-155, 1993.

Vaden SL, Page RL, Peters BP, Cline JM, Riviere JE: Development and characterization of an isolated and perfused tumor and skin preparation for evaluation of drug disposition. Cancer Research, 53: 101-105, 1993.

Monteiro-Riviere NA: The use of isolated perfused skin in dermatotoxicology. In Vitro Toxicology, 5: 219-233, 1992.

Spoo JW, Rogers RA, Monteiro Riviere NA: Effects of formaldehyde, DMSO, benzoyl peroxide, and sodium lauryl sulfate on isolated perfused porcine skin. In Vitro Toxicology, 5:251-260, 1992.

Monteiro-Riviere NA: Langerhans granules do exist in the porcine epidermis. Journal of Anatomy, 180:555-556, 1992.

Riviere JE: New models in skin research: the isolated perfused porcine skin flap. Wang R, Knack J, Maibach H (Eds). Health Risk Assessment: Dermal and Inhalational Exposure and Absorption of Toxicants, Boca Raton, CRC Press, pp. 439-452, 1992.

King JR, Riviere JE, Monteiro-Riviere NA: Characterization of lewisite toxicity in isolated perfused porcine skin. Toxicology Applied Pharmacology, 116:189-201, 1992.

Riviere JE: Dermal absorption and metabolism of xenobiotics in food producing animals. In Hutson DH, Hawkins DR, Paulson GD, Struble CR, (Eds). Xenobiotics in Food Producing Animals: Metabolism and Residues Washington: American Chemical Society: Symposium Series 503, pp.88-97, 1992.

Sage BH, Riviere JE: Model systems in iontophoresis transport efficacy. Advanced Drug Delivery Review, 9:265-287, 1992.

Srikrishna V, Riviere JE, Monteiro-Riviere NA: Cutaneous toxicity and absorption of paraquat in porcine skin. Toxicology Applied Pharmacology, 115:89-97, 1992.

Riviere JE, Williams PL: Pharmacokinetic implications of changing blood flow in the skin. Journal of Pharmaceutical Science, 81:601-602, 1992.

Riviere JE, Williams PL, Hillman R, Mishky L: Quantitative prediction of transdermal iontophoretic delivery of arbutamine in humans using the in vitro isolated perfused porcine skin flap (IPPSF). Journal of Pharmaceutical Science, 81:504-507, 1992.

Dewoskin, RS, Riviere JE: Cisplatin-induced loss of kidney copper and nephrotoxicity is ameliorated by single dose diethyldithiocarbamate, but not mesna. Toxicology Applied Pharmacology, 112:182-189, 1992.

Riond JL, Riviere JE, Duckett WM, Atkins CE, Jernigan AD, Rikihisa J, Spurlock SL: Cardiovascular effects and fatalities associated with intravenous administration of doxycycline to horses and ponies. Equine Veterinary Journal, 24:41-45, 1992.

Riviere JE, Monteiro-Riviere NA, Inman AO: Determination of lidocaine concentration in skin after transdermal iontophoresis: effects of vasoactive drugs. Pharmaceutical Research, 9:211-214, 1992.

Riviere JE, Chang S: Transdermal penetration and metabolism of organophosphate insecticides. In: Chambers JE, Levi PL: Organophosphates: Chemistry, Fate and Effects, New York, Academic Press. pp. 241-253, 1992.

Riviere JE: Practical aspects of the pharmacology of drug residue prevention in food animals. Agri-Practice, 13:11-16, 1992.

Monteiro Riviere NA: Comparative Anatomy, Physiology, and Biochemistry of Mammalian Skin. Dermal and Ocular Toxicology: Fundamentals and Methods (Ed. DW Hobson). CRC Press, Inc. Chapter 1, pp. 3-71, 1991.

Srikrishna V, Monteiro-Riviere NA: The effects of sodium hydroxide and hydrochloric acid on isolated perfused skin. In Vitro Toxicology, 4:207-215, 1991.

King JR, Monteiro Riviere NA: Effects of organic solvent vehicles on the viability and morphology of isolated perfused porcine skin. Toxicology, 69:11-26, 1991.

Monteiro Riviere NA, Banks YB, Birnbaum LS: Laser doppler measurements of cutaneous blood flow on aging mice and rats. Toxicology Letters, 57:329-338, 1991.

Riviere JE, Monteiro-Riviere NA: Skin: porcine skin flaps. In Vitro Biological Systems: Preparation and Maintenance. (Eds. CA Tyson and JM Frazier). Academic Press, Inc, FL. Chapt.45,515-524, 1991.

Manning TO, Monteiro-Riviere NA, Bristol DG, Riviere JE: Cutaneous laser doppler velocimetry in nine animal species. American Journal of Veterinary Research, 52:1960-1964, 1991.

Bristol DG, Riviere JE, Monteiro Riviere NA, Bowman KF, Rogers RA: The isolated perfused equine skin flap: preparation and metabolic parameters. Vet. Surg., 20:424-433, 1991.

Shah VP et al. (with Anderson BD, Riviere JE et al.): In vivo percutaneous penetration/absorption. Pharmaceutical Research. 8:1071-1075, 1991 and Skin Pharmacology, 4:220-228, 1991.

King JR, Riviere JE, Monteiro-Riviere NA: Characterization of lewisite vesication in isolated perfused porcine skin. Proceedings of the 1991 Medical Defense Bioscience Review, pp. 167-170, 1991.

Riviere JE, King JR, Monteiro-Riviere NA: Characterization of the cutaneous vascular response to topically applied sulfur mustard and lewisite. Proceedings of the 1991 Medical Defense Bioscience Review, pp. 163-166, 1991.

Monteiro-Riviere NA, King JR, Riviere JE: Mustard induced vesication in isolated perfused skin: biochemical, physiological and morphological studies. Proceedings of the 1991 Medical Defense Bioscience Review, pp. 159-162, 1991.

Riviere JE, Monteiro-Riviere NA: The isolated perfused porcine skin flap as an in vitro model for percutaneous absorption and cutaneous toxicology. Critical Reviews in Toxicology, 21:329-344, 1991.

Riviere JE: Perspectives on the information needs of the agricultural researcher of the 21st century. Adv. Library Administration Organization, 9:239-248, 1991.

Riviere JE, Page RL, Aucoin DP, Rogers RA, Williams, PL: Effect of hyperthermia on the in vitro hydrolysis of melphalen. Int. Journal of Hyperthermia, 7:527-529, 1991.

Chang SK, Riviere JE: Percutaneous absorption of parathion in vitro in porcine skin. Effects of dose, temperature, humidity and perfusate composition on absorptive flux. Fundamental Applied Toxicology, 17:494-504, 1991.

Riviere JE, Sage BS, Williams PL: The effects of vasoactive drugs on transdermal lidocaine iontophoresis. Journal of Pharmaceutical Science, 80:615-620, 1991.

Bowman KF, Monteiro Riviere NA, Riviere JE: Development of surgical techniques for preparation of in vitro isolated perfused porcine skin flaps for percutaneous absorption studies. American Journal of Veterinary Research, 52:75-82, 1991.

Riviere JE: In vitro absorption skin flap model in Bronaugh RL, Maibach HI (Eds). In vitro Percutaneous Absorption Principles, Fundamentals and Applications, Boca Raton, CRC Press. pp. 207-222, 1991.

Riviere JE, Carver MP: Isolated perfused skin flap and skin grafting techniques. In Hobson DW (Ed.): Dermal and Ocular Toxicology Fundamentals and Methods: Boca Raton CRC Press, pp. 297-322, 1991.

Riviere JE: Pharmacologic principles of residue avoidance for the practitioner. Journal of American Veterinary Medical Association, 198:809-816, 1991.

Brown SA, Riviere JE: Comparative pharmacokinetics of aminoglycoside antibiotics. Journal Veterinary Pharmacology Therapeutics, 14:1-35, 1991.

Monteiro Riviere NA, Bristol DG, Manning TO, Rogers RA, Riviere JE: Interspecies and interegional analysis of the comparative histological thickness and laser Doppler blood flow measurements at five cutaneous sites in nine species. Journal of Investigative Dermatology, 95:582-586, 1990.

Monteiro Riviere NA: Specialized Technique: Isolated Perfused Porcine Skin Flap. Methods for Skin Absorption (Eds. BW Kemppainen and WG Reifenrath). CRC Press, Inc. Chapter 11, pp. 175-189, 1990.

King JR, Monteiro Riviere NA: Cutaneous toxicity of 2 chloroethyl methyl sulfide in isolated perfused porcine skin. Toxicology and Applied Pharmacology, 104:167-179, 1990.

Monteiro-Riviere NA: Altered epidermal morphology secondary to lidocaine iontophoresis: in vitro and in vivo studies in porcine skin. Fundamental and Applied Toxicology, 15:174-185, 1990.

Carver MP, Levi PE, Riviere JE: Parathion metabolism during percutaneous absorption in perfused porcine skin. Pesticide Biochemical Physiology, 38:245-254, 1990.

Williams PL, Fitch, WM: Phylogeny determination using dynamically weighted parsimony method. Methods in Enzymology, 183:615-625, 1990.

Williams PL: Structural identifiability of pharmacokinetic models-compartments and experimental design. Journal Veterinary Pharmacology Therapeutics, 13:121-131, 1990.

Riond JL, Vaden SL, Riviere JE: Comparative pharmacokinetics of doxycycline in cats and dogs. Journal Veterinary Pharmacology Therapeutics, 13:415-424, 1990.

Riond JL, Riviere JE: Allometric analysis of doxycycline pharmacokinetic parameters. Journal Veterinary Pharmacology Therapeutics, 13:404-407, 1990.

Riond JL, Riviere JE: Pharmacokinetics and metabolic inertness of doxycycline in young pigs. American Journal Veterinary Research 51:1271-1275, 1990.

Williams PL, Riviere JE: Effect of hyperthermia on cisplatin (CDDP) disposition to isolated perfused skin. Int. Journal of Hyperthermia 6:923-932, 1990.

Tyczkowska K, Page RL, Riviere JE: Determination of carboplatin in canine plasma by liquid chromatography with ultraviolet-visible detection and confirmation by atomic absorption spectroscopy. Journal of Chromatography 527:447-453, 1990.

Riviere JE, Page RL, Rogers RA, Chang SK, Dewhirst MW, Thrall DE: Non-uniform alteration of cis-diamminedichloroplatinum (II) tissue distribution in dogs with whole body hyperthermia. Cancer Research50:2075-2080, 1990.

Williams PL, Carver MP, Riviere JE: A physiologically relevant pharmacokinetic model of xenobiotic percutaneous absorption utilizing the isolated perfused porcine skin flap (IPPSF). Journal of Pharmacology Sciences 79:305-311, 1990.

Vaden SL, Riviere JE: Pharmacokinetics, inhibition of lymphoblast transformation and subacute oral toxicity of cyclosporine in clinicall normal pigs. American Journal of Veterinary Research 51:399-403, 1990.

Kimmel CA, Francis EZ (with Bui Q, DePass L, Guest D, Johnson GR, Riviere JE, Schardin J, Schwetz BA, Shah PV, Tye R, Young JF): Proceedings of the workshop on the acceptability and interpretation of dermal developmental toxicity studies. Fundamental Applied Toxicology 14:386-398, 1990.

Riviere JE, Monteiro-Riviere NA: Percutaneous absorption of pesticides in the isolated perfused porcine skin flap (IPPSF). In Tscharner C, Halliwell REW (Eds.) Advances in Veterianary Dermatology I, Balliere-Tindall, London. pp. 299-307, 1990.

Riviere JE: Biological factors in absorption and penetration. Cosmetics Toiletries 105:85-93, 1990.

Vaden SL, Riviere JE: An isolated perfused tumored skin flap model. Veterinary Cancer Society Newsletter 14:1-6, 1990.

Williams, PL. Structural identifiability of pharmacokinetic models--compartments and experimental design. J. Vet. Pharmacol. Therap. 13: 121-131, 1990.

Riviere JE, Sage B, Monteiro-Riviere NA: Transdermal lidocaine iontophoresis in isolated perfused porcine skin. Journal of Toxicology, Cutaneous and Ocular Toxicology 8:493-504, 1989/90.

Carver MP, Riviere JE: Percutaneous absorption and excretion of xenobiotics after topical and intravenous administration to pigs. Fundamental Applied Toxicology 13:714-722, 1989.

Williams PL, Riviere JE: Estimation of physiological volumes in the isolated perfused porcine skin flap. Research Communications Chemical Pathology Pharmacology 66:145-158, 1989.

Williams PL, Riviere JE: Definition of a physiologic pharmacokinetic model of cutaneous drug distribution using the isolated perfused porcine skin flap (IPPSF). Journal of Pharmacology Science 78:550-555, 1989.

Page RL, Riviere JE, Heidner GL, McEntee MC, Thrall DE: Effect of temperature on cisplatin (CDDP) and carboplatin (CBDCA) pharmacokinetic disposition in dogs. Proc. 5th Int. Symp. Hyperthermic Oncology, Vol. 2. London: Taylor and Francis, pp. 499-501, 1989.

Monteiro Riviere NA, King JR: The dermatotoxicity of 2 chloroethyl methyl sulfide and solvent vehicles in isolated perfused porcine skin. Proceedings of the 1989 Medical Defense Bioscience Review. pp. 53 56, 1989.

Carver MP, Williams PL, Riviere JE: The isolated perfused porcine skin flap (IPPSF). III. Percutaneous absorption pharmacokinetics of organophosphates, steroids, benzoic acid and caffeine. Toxicology Applied Pharmacology 97:324-337, 1989.

Riond, J-L, Tyczkowska, K, and Riviere, JE, Pharmacokinetics and metabolic inertness of doxyxycline in calves with mature or immature rumen function. Am. J. Vet. Res. 50(8): 1329-1333, 1989.

Riond, J-L, and Riviere, JE, Doxycycline binding to plasma albumin of several species. J. Vet. Pharmacol. Therap. 12: 253-260, 1989.

Riond, J-L, Hedeen, KM, Tyczkowska, K, and Riviere, JE. Determination of doxycycline in bovine tissues and body fluids by high-performance liquid chromatography using photodiode array ultraviolet-visible detection. J. Pharm. Sci. 78(1) 44-47, 1989.

Riviere JE: Development of an in vitro perfused skin flap model for transdermal drug delivery studies. Workshop on Transdermal Delivery of Drugs, NIH-NICHHD, Bethesda, MD, 1988.

Riviere JE: Development of perfused skin models for assessing xenobiotic percutaneous absorption. Burroughs Wellcome Symposium on Dermal Toxicology, pp. 28-40, 1988.

Riond, J-L, and Riviere, JE, Multiple intravenous dose pharmacokinetics and residue depletion profile and gentamicin in pigs. J. Vet. Pharmacol. Therap. 11: 210-214, 1988.

Riond, J-L, and Riviere, JE, Pharmacology and toxicology of doxycycline. Vet. Hum. Toxicol. 30(5): 431-443, 1988.

Frazier, DL, Aucoin, DP, and Riviere, JE. Gentamicin pharmacokinetics and nephrotoxicity in naturally acquired and experimentally induced disease in dogs. JAVMA 192(1): 57-63, 1988.

Riviere JE: The isolated perfused porcine skin flap. Bernstein EM: Humane Innovations and Alternatives in Animal Experimentation: A Notebook Psychologists for the Ethical Treatment of Animals, Saranac Lake, NY, pp. 7, 1987.

Monteiro Riviere NA, Manning TO: The effects of different fixatives on the porcine integument. 45th Annual Proceedings, Electron Microscopy Society of America, (Ed. G.W. Bailey). San Francisco Press. pp. 948 949, 1987.

Riviere JE, Carver MP, Monteiro NA, Bowman KF: Percutaneous absorption of organophosphates, steroids, caffeine and benzoic acid in vivo and in vitro using the isolated perfused porcine skin flap (IPPSF). 6th Medical Chemical Defense Bioscience Review, pp. 763-766, 1987.

Monteiro-Riviere NA, Bowman KF, Scheidt VJ, Riviere JE: The isolated perfused porcine skin flap (IPPSF): II. Ultrastructural and histological characterization of epidermal viability. In Vitro Toxicology 1:241-252, 1987.

Zakris EL, Dewhirst MW, Riviere JE, Hoopes PJ, Oleson JR: Pharmacokinetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia. Journal of Clinical Oncology 5:1613-1620, 1987.

Riviere JE, Bowman KF, Monteiro-Riviere NA: On the definition of viability in isolated perfused skin preparations. Brit. J. Dermatol. 116:739-741, 1987.

Frazier, DL, and Riviere, JE., Gentamicin dosing strategies for dogs with subclinical renal dysfunction. Antimicrobial Agents and Chemotherapy, 31(12): 1929-1934, 1987.

Rogers, RA, Hanna, AY, Riviere, JE. Dose response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. III. Effects of dosage adjustment method. Res. Comm. in Chem. Path. and Pharm. 57(3): 301-311, 1987.

Riond, J-L, and Riviere, JE, L'usage de la gentamicin en medecine veterinaire: une revue de la literature. Schwiez. Arch. Teirheilk. 129: 565-583, 1987.

Riviere JE, Carver MP, Monteiro-Riviere NA, Bowman KF: Development of in vitro isolated perfused porcine skin flaps for study of percutaneous absorption of xenobiotics. DAMD17-84C-4103. NTIS, ADA198960, pp. 1-23, 1986.

Monteiro Riviere NA: Ultrastructural evaluation of the porcine integument. Swine in Biomedical Research (Ed. ME Tumbleson). Plenum Publishing Corporation. 1:641 655, 1986.

Riviere JE, Bowman KF, Monteiro-Riviere NA: The isolated perfused porcine skin flap: A novel animal model for cutaneous toxicologic research. Swine in Biomedical Research (Ed. ME Tumbleson). Plenum Publishing Corporation. 1:657 666, 1986.

Riviere JE, Bowman KF, Monteiro-Riviere NA, Carver MP, Dix LP: The isolated perfused porcine skin flap (IPPSF). I. A novel in vitro model for percutaneous absorption and cutaneous toxicology studies. Fundamental Applied Toxicology 7:444-453, 1986.

Riviere JE, Page RL, Dewhirst MW, Tyczkowska K, Thrall DE: Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs. Int. J. Hyperthermia, 2:351-358, 1986.

Frazier DL, Dix LP, Bowman KF, Thompson C, and Riviere JE: Increased gentamicin nephrotoxicity in normal and diseased dogs administered identical serum drug concentration profiles: Increased sensitivity in subclinical renal dysfunction. J. Pharmac. and Experim. Therapeutics 239(3): 946-951, 1986.

Dix, LP, Frazier, DL, Cooperstein, M, and Riviere, JE. Exponential intravenous infusion in toxicological studies: Achieving identical serum drug concentration profiles in individuals with altered pharmacokinetic states. J. Pharm. Sci. 75(5): 448-452, 1986.

Monteiro-Riviere NA, Popp JA: Ultrastructural evaluation of acute nasal toxicity in the rat respiratory epithelium in response to formaldehyde gas. Fundamental and Applied Toxicology 6: 251-262, 1986.

Riviere JE, Dix LP, Carver MP, and Frazier DL. Identification of a subgroup of Sprague-Dawley rats highly sensitive to drug-induced renal toxicity. Fundamental and Applied Toxicology 7: 126-131, 1986.

Riviere JE, Craigmill AL, Sundlof SF: Food animal residue avoidance databank (FARAD): An automated pharmacologic databank for drug and chemical residue avoidance. Journal of Food Protection 49: 826-830, 1986.

Frazier DL, Carver MP, Dix LP, Thompson CA, and Riviere JE: Exaggerated response to gentamicin-induced nephrotoxicity in Sprague-Dawley rats: Identification of a highly sensitive outlier population. Toxicologic Pathology 14: 204-209, 1986.

Brown SA, Riviere JE., Coppoc GL, and Dix LP. Superiority of the power function over exponential functions for prediction of renal gentamicin residues in sheep. Journal of Veterinary Pharmacology Therapy: 341-346, 1986.

Riond J-L, Dix LP, and Riviere JE: Influence of thyroid function on the pharmacokinetics of gentamicin in pigs. American Journal of Veterinary Research 47: 2141-2146, 1986.

Monteiro-Riviere NA, Stromberg MW: Ultrastructure of the integument of the domestic pig (Sus scrofa) from one through fourteen weeks of age. Zbl. Vet. Med. C. Anat. Histol. Embryol. 14, 97-115, 1985.

Riviere JE, Bowman KF, Rogers RA: Decreased fractional renal excretion of gentamicin in subtotal nephrectomized dogs. Journal of Pharmacology and Experimental Therapeutics 234: 90-93, 1985.

Carver MP, Monteiro-Riviere NA, Brown TT, and Riviere JE: Dose-response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. II. Polyvinyl alcohol Glomerulopathy. Toxicology and Applied Pharmacology 80: 264-273, 1985.

Carver MP, Shy-Modjeska JS, Brown TT, Rogers RA, Riviere JE: Dose-response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. Toxicology and Applied Pharmacology 80: 251-263, 1985.

Riviere JE, Davis LE: Renal handling of drugs in renal failure. Canine Nephrology Book chapter 28, pp. 643-685, 1985.

Riviere JE: Adverse drug reactions in cats with feline urethral obstruction. Veterinary Clinics of North America: Small Animal Practice 14: 703-709, 1984.

Riviere JE: Calculation of dosage regimens of antimocrobial drugs in animals with renal and hepatic dysfunction. Journal of the American Veterinary Medical Association 185: 1094-1097, 1984.

Riviere JE, Carver MP: Effects of familial hypothyroidism and subtotal surgical nephrectomy an gentamicin pharmacokinetics in beagle dogs. Chemotherapy 30: 216-220, 1984.

Dix LP, Bai SA, Rogers RA, Anderson DL, Riviere JE: Pharmacokinetics of digoxin in sheep: Limitations of the use of biological half-life for interspecies extrapolation. American Journal of Veterinary Research 46:470-472, 1984.

Riviere JE, Carver MP, Coppoc GL, Carlton WW, Lantz GC, Shy-Modjeska J: Pharmacokinetics and comparative nephrotoxicity of fixed-dose versus fixed-interval reduction of gentamicin dosage in subtotal nephrectomized dogs. Toxicology and Applied Pharmacology 75:496-509, 1984.

Shy-Modjeska JS, Riviere JE, Rawlings JO: Application of biplot methods to the multivariate analysis of toxicological and pharmacokinetic data. Toxicology and Applied Pharmacology 72:91-101, 1984.

Riviere JE, Coppoc GL, Hinsman EJ, Carlton WW, Traver DS: Species dependent gentamicin Pharmacokinetics and nephrotoxicity in the young horse. Fundamental and Applied Toxicology 3:448-457, 1983.

Riviere JE, Traver DS, Coppoc, GL: Gentamicin toxic nephropathy in horses with disseminated bacterial infection.Journal of the American Veterinary Medical Association 180:648-651, 1982.

Riviere JE: Paradoxical increase in aminoglycoside body clearance in renal disease when volume of distribution increases. Journal of Pharmaceutical Sciences 71:720-721, 1982.

Riviere JE: Limitations on the physiologic interpretation of aminoglycoside body clearance derived from pharmacokinetic studies.Research Communications in Chemical Pathology and Pharmacology 38:31-42, 1982.

Stromberg MW, Hwang YC, Monteiro-Riviere NA: Interfollicular smooth muscle in the skin of the domesticated pig.The Anatomical Record 201:455-462, 1981.

Monteiro-Riviere NA, Hwang YC,Stromberg MW: Light microscopic morphology of low resistance skin points in the guinea pig. American Journal of Chinese Medicine 9:155-163, 1981.

Riviere JE, Kaufman GM, Bright RM: Prophylactic use of systemic antimicrobial drugs in surgery. Continuing Education Article #5 3:345-354, 1981.

Riviere JE, Coppoc GL: Determination of cerebrospinal fluid gentamicin in the beagle using an indwelling cerebral ventricular cannula.Chemotherapy 27:309-312, 1981.

Riviere JE, Silver GR, Coppoc GL, Richardson RC: Gentamicin aerosol therapy in 18 dogs: Failure to induce detectable serum concentrations of the drug. Journal of the American Veterinary Medical Association 179: 166-168, 1981.

Riviere JE, Hinsman EJ, Coppoc GL, Carlton WW: Single dose gentamicin nephrotoxicity in the dog: Early functional and ultrastructural changes. Research Communications in Chemical Pathology and Pharmacology 33: 403-418, 1981.

Riviere JE, Coppoc GL, Hinsman EJ, Carlton WW: Gentamicin pharmacokinetic changes in induced acute canine nephrotoxic glomerulonephritis. Antimicrobial Agents and Chemotherapy 20: 387-392, 1981.

Traver DS, Riviere JE: Ampicillin in mares: A comparison of intramuscular sodium ampicillin or sodium ampicillin-ampicillin trihydrate injection. American Journal of Veterinary Research 43: 402-404, 1981.

Riviere JE, Coppoc GL: Pharmacokinetics of gentamicin in the juvenile dog. American Journal of Veterinary Research 42:1621-1623, 1981.