Faculty

Anthony Blikslager, DVM, PhD, DACVS
Associate Professor, Equine Surgery

PhD in Physiology (Gastroenterology), May 1997
North Carolina State University, Raleigh, NC

Doctor of Veterinary Medicine, May 1989
Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA

Phone: 919.513.7725
FAX: 919.513.6717
Email: anthony_blikslager@ncsu.edu

Specialty

Equine soft tissue surgery

Professional Experience & Qualifications

Diplomate, American College of Veterinary Surgeons, 1995
Editorial Review Board, Veterinary Surgery, 1995-1999
Editorial Review Board, American Journal of Veterinary Research, 1999-2002.
Resident, Large Animal Surgery, July 1990-July 1994
North Carolina State University, College of Veterinary Medicine, Raleigh, NC
Intern, Equine Medicine and Surgery, June 1989-June 1990
University of Missouri, Equine Center, Columbia, MO.

Research Area

Gastrointestinal Physiology, studying mechanisms responsible for maintenance and restoration of the intestinal barrier, with the ultimate objective of pharmacologically restoring the mucosal barrier in patients suffering from diseases associated with increased intestinal permeability. Restoring the intestinal barrier would be of particular significance in patients suffering from diseases such as intestinal ischemia/ reperfusion injury because of the rapid onset of sepsis and multiple organ failure associated with translocation of bacteria and associated toxins across damaged intestinal epithelium. More

Selected Publications

Original Research

Little D, Tomlinson JE, Blikslager AT. Post operative neutrophilic inflammation in equine small intestine after manipulation and ischaemia. Equine Vet J 2005;37:329-35.

Tschetter JR, Blikslager AT, Little D, Howard RD, Woody SL, Beex LM, Crisman MV. Detection of differentially regulated genes in ischaemic equine intestinal mucosa. Equine Vet J 2005;37:319-24.

Little D, White CE, Young KM, Blikslager AT. Faecal bile loss in horses following small intestinal resection. Equine Vet J 2005;37:92-4.

Tomlinson JE, Blikslager AT. Effects of the cyclooxygenase inhibitors flunixin and deracoxib on permeability of ischaemic-injured equine jejunum. Equine Vet J , 2005;37:75-80.

Campbell NB, Ruaux CG, Shifflett DE, Steiner JM, Williams DA, Blikslager AT. Physiologic concentrations of bile salts inhibit recovery of ischemic-injured porcine ileum. Am J Physiol Gastrointest Liver Physiol 2004;287:G399-407

Tomlinson JE, Wilder BO, Young KM, Blikslager AT. Systemic administration of flunixin meglumine or etodolac inhibits mucosal recovery of equine jejunum after ischemia. Am J Vet Res 2004;65:761-769.

Tomlinson JE, Blikslager AT. Effects of ischemia and the cyclooxygenase inhibitor flunixin on in vitro passage of lipopolysaccharide across ischemic-injured equine jejunum. Am J Vet Res 2004;65:1311-1450.

Review Articles in Peer-reviewed Journals

Blikslager AT, Jones SL. NSAIDs. J Equine Vet Sci 2005;25:98-102

Blikslager AT. What COX-1 and COX-2 do and how they differ. Vet Forum 2005;Oct:23-28.

Blikslager AT. Management of pain in horses with colic. Comp Stand Care 2001;1:7-12.

Books and Book Chapters

Blikslager AT, Jones SL, Grondhal ML, Merritt AM, and Malbert CH. Pathophysiology of the Gastrointestinal Tract. In: Dunlop C, Malbert CH, Eds., Veterinary Pathophysiology, Blackwell Publishing, Ames, 2004, pp. 111-142

Blikslager AT. Treatment of ischemic intestinal disease. Vet Clin North Am 2003;19:715-728.

Jones SL, Blikslager AT. Esophageal diseases. In: Reed S, Bayly W, Sellon D., Eds., Equine Internal Medicine, Harcourt, St. Louis, 2003, 855-863.

Blikslager AT, Jones SL. Ischemic disorders of the intestinal tract. In: Reed S, Bayly W, Sellon D., Eds., Equine Internal Medicine, Harcourt, St. Louis, 2003, 913-922.

Blikslager AT, Jones SL. Obstructive disorders of the intestinal tract. In: Reed S, Bayly W, Sellon D., Eds., Equine Internal Medicine, Harcourt, St. Louis, 2003, 922-936.

Blikslager AT. Pathophysiology of Mucosal Injury and Repair. In: Reed S, Bayly W, Sellon D., Eds., Equine Internal Medicine, Harcourt, St. Louis, 2003, 802-815.

Links

Gastrointestinal Physiology Laboratory

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