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Christopher L. Mariani, DVM, PhD, DACVIM

Christopher L. Mariani

Associate Professor, Neurology
Phone: 919.513.0302
Fax: 919.513.6714
Email: chris_mariani@ncsu.edu

Education

Bachelor of Science (BSc), College of Biological Science, 1996, University of Guelph, Guelph, Ontario, Canada
Doctor of Veterinary Medicine (DVM), 1996, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
Doctor of Philosophy (PhD), 2006, College of Medicine, University of Florida, Gainesville, Florida

Specialty

Small Animal Neurology and Neurosurgery

Professional Experience & Qualifications

Diplomate, American College of Veterinary Internal Medicine (Neurology), 2001

Adjunct Clinical Professor of Neurology and Neurosurgery, College of Veterinary Medicine, University of Florida, Gainesville, Florida, 2001-2006

Residency in Neurology and Neurosurgery, College of Veterinary Medicine, University of Florida, 1998-2001

Associate Veterinarian, Beverly Hills Veterinary Associates, Beverly Hills, Michigan, 1997-1998

Rotating Internship in Small Animal Medicine, Surgery, Emergency and Critical Care, Michigan Veterinary Specialists, Southfield, Michigan, 1996-1997

Research Area

Selected Publications

Refereed Journals

Musulin SE, Mariani CL, Papich MG.  Diazepam pharmacokinetics after nasal drop and atomized nasal adminstration in dogs. Journal of Veterinary Pharmacology and Therapeutics, 2010, In Press.

Reitman ZJ, Olby NJ, Mariani CL, Thomas R, Breen M, Bigner DD, McLendon RE, Yan H.  IDH1 and IDH2 hotspot mutations are not found in canine glioma.  International Journal of Cancer, 2009 Epub Oct 29, DOI 10.1002/ijc.25017.

Sessums K, Mariani CL.  Intracranial Meningioma in dogs and cats. A comparative review. Compendium of Continuing Education for Veterinarians, 2009;31(7):330-339.

Levkoff LH, Marshall GP, Ross HH, Calderia M, Reynolds BA, Cakiroglu M, Mariani CL, Streit WJ, Laywell ED.  Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo.  Neoplasia, 2008;10(8):804-816.

Holawaychuk, MK, Hansen, BG, Hanel RM, Marks SL, Mariani CL.  Head Trauma.  Standards of Care, Emergency and Critical Care Medicine.  2007;9(6):1-8,16.

Mariani CL.  The neurologic examination and neurodiagnostic techniques for reptiles.  Veterinary Clinics of North America Exotic Animal Practice, 2007;10:855-891.

Mariani CL, Rajon D, Bova FJ, Streit WJ.  Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas. Journal of Neuro-oncology, 2007;85(3):231-240.

Wong M, Mariani CL, Powe J, Clemmons RM.  Teratoma in the cervical spinal cord of a dog.  Journal of the American Animal Hospital Association, 2007;43:292-297.

Mariani CL , Kouri JG, Streit WJ. Rejection of RG-2 gliomas is mediated by microglia and T lymphocytes. Journal of Neuro-oncology, 2006;79:243-253.

Streit WJ, Conde JR, Fendrick SE, Flanary BE, Mariani CL. Role of microglia in the central nervous system's immune response. Neurological Research, 2005; 27:685-691.

Barnes HL, Chrisman CL, Mariani CL, Sims M, Allemand AR. Clinical signs, underlying cause and outcome in cats with seizures: 17 cases (1997-2002). Journal of the American Veterinary Association 2004; 225:1723-1726.

Mariani CL. Full recovery following d elayed neurologic signs after smoke inhalation in a dog. Journal of Veterinary Emergency and Critical Care 2003;13:235-239.

Thompson MS, Graham JP, Mariani CL. Diagnosis of a porto-azygyous shunt using helical computed tomography angiography. Veterinary Radiology & Ultrasound 2003;44:287-291.

Mariani CL, Platt SR, Scase TJ, Howerth EW, Chrisman CL, Clemmons RM. Cerebral phaeohyphomycosis caused by Cladosporium spp . in two domestic short-haired cats. Journal of the American Animal Hospital Association 2002; 38:225-230.

Mariani CL, Platt SR, Newell SM, Terrell SP, Chrisman CL, Clemmons RM. Magnetic resonance imaging of cerebral cortical necrosis (polioencephalomalacia) in a dog. Veterinary Radiology & Ultrasound 2001; 42:524-531.

Mariani CL, Clemmons RM, Graham JP, Phillips LA, Chrisman CL. Magnetic resonance imaging of spongy degeneration of the central nervous system in a Labrador retreiver. Veterinary Radiology & Ultrasound 2001; 42:285-290.

Mariani CL, Fulton RB Jr. Atypical reaction to acetaminophen intoxication in a dog. Journal of Veterinary Emergency and Critical Care 2001; 11:123-126.

Mariani CL, Shelton SB, Alsup JC. Paraneoplastic polyneuropathy and subsequent recovery following tumor removal in a dog. Journal of the American Animal Hospital Association 1999; 35:302-305.

Books and Book Chapters

Mariani CL.  Tumours of the Nervous System.  In:  Lascelles BDX and Dobson JM.  BSAVA Manual of Canine and Feline Oncology, 3rd edition.  In Press.

Mariani CL.  Neuromuscular Junction Disease.  In:  Ettinger SJ and Feldman EC, eds.  Textbook of Veterinary Internal Medicine, 7th edition. St. Louis, MO: Saunders Elsevier; 2010:1473-1477.

Mariani CL.  Peripheral Nerve Disorders. In:  Ettinger SJ and Feldman EC, eds.  Textbook of Veterinary Internal Medicine, 7th edition. St. Louis, MO: Saunders Elsevier; 2010:1462-1467.

Chrisman CL, Mariani CL, Platt SR, Clemmons RM. Neurology for the Small Animal Practitioner. Jackson : Teton NewMedia, 2003;1-353.

Mariani CL. Dancing Doberman Disease. In: CD Canis. Kansas City: Vetstream, Inc., 2004.

Mariani CL. Spongy Degeneration. In: CD Canis. Kansas City: Vetstream, Inc., 2003.