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Adam Moeser, DVM, PhD

Moeser

Gastrointestinal Biology and Swine Medicine
Associate Professor

Office: 406, CVM Research Building
Phone: 919.513.0711
Fax: 919.515.3044
Email: ajmoeser@ncsu.edu

Course Involvement

Graduate Courses

Undergraduate Courses

Education/Training

Honors and Awards

Research

Stress and Gastrointestinal Biology. Stress is an important trigger in the onset and exacerbation of gastrointestinal (GI) diseases of humans and animals. Despite the well-accepted role of stress in GI disease susceptibility, the underlying pathogenic mechanisms remain poorly understood and thus no definitive curative therapies are available. The long-term goal of my research program is to gain a fundamental understanding of the biological mechanisms by which stress impacts the development and clinical severity of important GI diseases. Specifically, our research is focused on the following areas:

• The role and mechanisms of corticotropin releasing factor (CRF) receptors on mast cells in allergic and GI disease

• Stress-induced regulation of intestinal epithelial barrier function

• Neuro-immune interactions in the gut as influenced by early life stress

• Role of mast cells in colitis

• Sex-specific responses in intestinal physiology and mast cell biology

We believe that this work could have important implications in the understanding of stress-
related gut disorders such as allergy/anaphylaxis, Inflammatory Bowel Disease, and Irritable Bowel Syndrome, and may facilitate the design of novel preventative and treatment strategies for veterinary and human patients suffering from these disorders.

Current Lab members

Funding support

Lab Press Releases/News

Selected publications