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Kevin Anderson, DVM, PhD

Kevin Anderson

Ruminant Health and
Production
Medicine
Professor

Office: D-261, CVM Main Building
Phone: 919.513.6245
Fax: 919.513.6464
Email: kevin_anderson@ncsu.edu

 


Course Involvement

  • VMP 916: Goat Production and Physical Examination Procedures
  • VMP 936: Sheep Production Cycle and Physical Examination Procedures (Fall)
  • VMP 936: Mastitis Detection, Therapy and Control (Spring)
  • VMP 956: Pregnancy Detection (Ultrasound) in Small Ruminants (Fall)
  • VMP 956: Small and Large Ruminant Section (Spring)
  • VMP 962: Course Faculty
  • VMP 970: Ruminant Health Management I
  • VMP 972: Ruminant Health Management II
  • VMP 974: Food Supply Veterinary Medicine
  • VMP 987: Ruminant Special Topics
  • VMF 991(101): Milk Quality for Veterinary Professionals
  • VMP 992(108): Small Ruminant Clinical Experience

Graduate Courses

  • FSA 520A: Pre-Harvest Food Safety

Undergraduate Courses

  • VMP 420: Diseases of Farm Animals

Education/Training

  • DVM, University of Minnesota
  • PhD, Veterinary Pathology, University of Illinois
  • MS, Veterinary Clinical Medicine, University of Illinois
  • Board Certification: Diplomate, American Board of Veterinary Practitioners (Dairy Specialty)

Research Area

Program focus: Improving the quality of milk from ruminants.

Basic research: Mastitis and milk quality in ruminant species are studied in this laboratory. This includes investigating the pathophysiology and epidemiology of mastitis as well as the detection and mitigation of antimicrobial residues in milk. Current mastitis research includes a study of Staphylococcus aureus mastitis using pulsed-field gel electrophoresis, herd data analysis, and antibiotic susceptibilities. We are participating in an investigation of a combined therapy-vaccination strategy to control and prevent Staphylococcus aureus mastitis. Current antimicrobial residue studies utilize a microbial receptor assay, HPLC, and other detection methods to measure residues and investigate alternative dispositions for antibiotic contaminated milk. The disposition of beta-lactam antibiotics in calves fed antibiotic-contaminated milk has been investigated, as well as methods to neutralize antibiotics in milk. Beta-lactam and tetracycline residues in milk after administration by several routes have been researched using microbial receptor assays and HPLC. Mastitis therapeutics have been investigated using mastitis challenge models. Additional interests focus on small ruminant and cattle health.

Selected Publications

Mullen KAE, KL Anderson, SP Washburn.  Effect of 2 herbal intramammary products on milk quantity and quality compared with conventional and no dry cow therapy.  J Dairy Sci, in press, March, 2014.

Mullen, KAE, AR Lee, RL Lyman, SE Mason, SP Washburn, KL Anderson.  An in vitro assessment of the antibacterial activity of plant-derived oils.  J Dairy Sci, Submitted and under review, December, 2013.

Mullen, KAE, LG Sparks, RL Lyman, SP Washburn, and KL Anderson.  Comparisons of milk quality on North Carolina organic and conventional dairies.  J Dairy Sci  2013/96/6753-6762.

Anderson KL, R Lyman, K Moury, D Ray, DW Watson, MT Correa.  Molecular epidemiology of Staphylococcus aureus mastitis in dairy heifers.  J Dairy Sci  2012/95/4921-4913.

Rivas, AL, MD Jankowski, R Piccinini, G Leitner, D Schwarz, KL Anderson, JM Fair, AL Hoogesteijn, W Wolter, M Chaffer, S Blum, T Were, SN Konah, P Kempaiah, JM Ong’echa, 3.  US Diesterbeck, R Pilla, C-P Czerny, JB Hittner, JM Hyman, DJ Perkins. Feedback-Based, System-Level Properties of Vertebrate-Microbial Interactions. PLoS ONE 2013/8(2)/e53984. doi:10.1371/journal.pone.0053984.

RO Azizoglu, R Lyman, KL Anderson.  Bovine Staphylococcus aueus:  Dose response to iodine and chlorhexidine and effect of iodine challenge on antibiotic susceptibility.  J Dairy Sci 96(2)/2013/993-999. http://dx.doi.org.prox.lib.ncsu.edu/10.3168/jds.2012-5857

Marks Stowe D, KL Anderson, JE Guy, KE Linder, CB Grindem.  A case of enzootic nasal adenocarcinoma in a ewe.  Case Reports in Veterinary Medicine.  Volume 2012/Article ID 347193/4 pages.  Doi:  10.1155/2012/347193/Accepted September 5, 2012.

Pinto Ferreira, J., M.T. Correa, R. Lyman, K.L. Anderson.  A review of methicillin-resistant Staphylococcus aureus (MRSA) in dairy cattle.  The Bovine Practitioner.  2012/46(1)/1-9.

Ferreira, J.P., K.L. Anderson, M.T. Correa, R. Lyman, F. Ruffin, L.B. Reller, and V.G. Fowler.  Transmission of MRSA between companion animals and infected human  patients.  PLoS One.  2011; 6(11).

Anderson KL, MT Correa, A Allen and RR Rodriguez.  Fresh cow mastitis monitoring on day 3 postpartum and its relationship to subsequent milk production.  J Dairy Sci 93:  5673-5683, 2010.

Freeman SR, MH  Poore, GA Young, KL Anderson.  Influence of calcium (0.6 or 1.2%) and phosphorus (0.3 pr 0.6%) content and ration on the formation of urolithogenic compounds in the urine of Boer-cross goats fed high-concentrate diets.  Sm Rum Res 93, 2010, 94-102.

McPhee CS, Anderson KL, Yeats JL, Mason SE, Barlow BM, Baynes RE.  Hot topic:  Milk and plasma disposition of thymol following intramammary administration of a phytoceutical mastitis treatment.  J Dairy Sci 2011 94:  1738-1743.                                               

Pinto Ferreira J, FowlerVG, Correa MT, Lyman R, Ruffin F, Anderson KL.  Transmission of methicillin-resistant Staphylococcus aureus (MRSA) between human and hamster.  J Clin Microbiol 2011 49(4):  1679-1680.  Published online ahead of print on 16 February 2011.

Luginbuhl, J.M., S. Pietrosemoli, J.M. Howell, and K.L. Anderson.  Alternatives to traditional anthelmintics to control gastrointestinal nematodes in grazing meat goats.  Arch Latinoam Prod Anim  www.alpa.org.ve/ojs.index/php18 (3-4):  113-122, 2010.

Rivas AL, Chowell G, Schwager, SJ, Fasina FO, Hoogesteijn AL, Smith, SD, Bisschop SP, Anderson KL, Hyman JM.   Lessons from Nigeria:  the role of roads in the geo-temporal progression of avian influenza (H5N1) virus.  Epidemiol Infect 2010 Feb; 138(2):  192-198.  Epub 2009 Aug 5.

Rivas, A. L., K.L.  Anderson, R. Lyman, S.D. Smith, S.J. Schwager.  Proof of concept of a method that assesses the spread of microbial infections with spatially explicit and non-spatially explicit data .           Int J Health Geograph 7:58-64, 2008.  http://www.ij-healthgeographics.com/content/7/1/58.

Rivas, A.L. S.J. Schwager, R.N. Gonzalez, F.W. Quimby,  K.L.  Anderson.  Multifactorial relationships between intramammary invasion by Staphylococcus aureus and bovine leukocyte markers.  Can J Vet Res 71:135-144, 2007.

Anderson K.L., R.L. Lyman:  Long-term persistence of specific genetic types of mastitis-causing Staphylococcus aureus on three dairies.  J Dairy Sci 80:4551-4556, 2006.

Anderson K.L., R.L. Lyman, S.M. Bodeis-Jones, D.G. White:  Genetic diversity and antimicrobial susceptibility profiles among mastitis-causing Staphylococcus aureus isolated from bovine milk samples.  Am J Vet Res 67(7):  1185-1191, 2006.

Smith G.W., R.L. Lyman, K.L.  Anderson:  Efficacy of vaccination and antimicrobial treatment to eliminate chronic intramammary Staphylococcus aureus infection in dairy cattle.  J Am Vet Med Assoc 228(3):  422-425, 2006.

Rivas, A.L., R. Tadevosyan, R.C. Gorewit, K.L.  Anderson, R. Lyman, R.N. Gonzalez.  Relationships between the phagocytic ability of milk macrophages and polymorphonuclear cells and somatic cell counts in uninfected cows.  Can J Vet Res  70(1):  68-74, 2006. 

Poulsen, K.P., M.P. Gerard, K.A. Spaulding, K.A. Geissler, K.L.  Anderson.  Bilateral renal agenesis in an alpaca cria.  Can Vet J 47(2):  159-161, 2006.

Hanway, W.H., A.P. Hansen, K.L.  Anderson, R.L. Lyman, J.E. Rushing.  Inactivation of penicillin G in milk using hydrogen peroxide.  J Dairy Sci 88:  466-469, 2005.

MacDonald, P.D.M., R.E. Whitwam, J.D. Boggs, J.N. MacCormack, K.L.  Anderson, J.W.

Reardon, J.R. Saah, L.M. Graves, S.B. Hunter, J. Sobel.  Outbreak of listeriosis among Mexican immigrants as a result of consumption of illicitly produced Mexican-style cheese. Clin Infec Dis 40:  677-82, 2005. 

Diaz, D.E., W.M. Hagler Jr., J.T. Blackwelder J.A. Eve, B.A. Hopkins, K.L.  Anderson,  F.T. Jones, L.W. Whitlow. Aflatoxin binders II:  Reduction of aflatoxin M1 in milk by sequestering agents of cows consuming aflatoxin in feed.   Mcyopathologia 157:   233-241, 2004.

Anderson, K.L., C. Brownie J.M. Luginbuhl, M. Mobley.  Drug use survey and evaluation of quality assurance training for meat goat producers.  Int J Applied Res Vet Med 2(4):  261-268, 2004

Musser J.M.B., K.L. Anderson, J.O. Boison: Comparison of microbial growth inhibition assays with high-pressure liquid chromatography for detection of experimentally incurred pencillin G residues in calves. Vet Ther 2(3): 136-143, 2002.

Anderson K.L., R.L. Lyman, W.A. Moats, A.P. Hansen, J.E. Rushing: Comparison of microbial receptor assay and liquid chromatography for determination of penicillin G and amoxicillin in milk powder. J AOAC Int 85(3): 546-550, 2002.

Boison J.O., K. Souster, C. Drury, J.B. Musser, K. Anderson: An HPLC method for the determination of penicillin G residues in veal calf liver tissues. J Liq Chromatogr Relat Technol 24(6): 881-892, 2001

Musser J.M.B., K.L. Anderson, J.O Boison: Tissue disposition and depletion of penicillin G after oral administration with milk in unweaned dairy calves. J Am Vet Med Assoc 219(3): 346-350, 2001

Musser J.M.B., K.L. Anderson: Bioavailability and disposition of sodium and procaine penicillin G (benzylpenicillin ) administered orally with milk to calves. J Vet Pharmol Therap 24: 161-169, 2001.

Rivas A.L., M. Bodis, J.L. Bruce, K.L. Anderson, R.F. Klein, R.N. Gonzalez, F.W. Quimby, C.A. Batt, D.H. Lein: Molecular epidemiologic features and antimicrobial susceptibility profiles of various ribotypes of Pseudomonas aeruginsoa isolated from humans and ruminants. Am J Vet Res 62: 864-868, 2001.

Gayle J.M, G.A. Burrell, K.L. Anderson, W.R. Redding, A.T. Blikslager: Deep digital flexor tenotomy for treatment of severe laminities in a cow. J Am Vet Med Assoc 219: 644-646, 2001.

Musser, J.M.B., K.L. Anderson, J.E. Rushing., W.A. Moats: Potential for milk containing Penicillin G or amoxicillin to cause residues in calves. J Dairy Sci 84: 126-133, 2001.

Musser J.M.B., K.L. Anderson, W.A. Moats: Screening method for identification of B-lactams in bovine urine by use of liquid chromatography and a microbial inhibition test. Am J Vet Res 62: 326-330, 2001.

Baynes R.E., M. Payne, T. Martin-Jimenez., A.R. Abdullah., K.L. Anderson, A.I. Webb., A. Craigmill., J.E. Riviere: Extralabel use of ivermectin and moxidectin in food animals. J Am Vet Med Assoc 217(5): 668-671, 2000.

Moats W.A., K.L. Anderson, J.E. Rushing, S. Buckley: Conversion of Cephapirin to deacetylcephapirin in milk and tissues of treated animals. J Agric Food Chem 48(2): 498-502, 2000.

Baynes, R.E., R. Lyman, K.L. Anderson, and C.F. Brownie: A preliminary survey of antibiotic residues and viable bacteria in milk from three Caribbean Basin countries. J Food Prot 62(2):177-180, 1999.

Howell, J.M., J-M Luginbuhl, M.J. Grice, K.L. Anderson, P. Arasu, and J.R. Flowers: Control of gastrointestinal parasite larvae of ruminant using nitrogen fertilizer, limestone and sodium hypochlorite solutions. Small Ruminant Research 32:197-204, 1999.

Musser, J.M.B., and K.L. Anderson: Using drug residue screening tests to investigate antibiotic contamination of milk. Vet Med 94(5):474-479, 1999 (May).

Musser, J.M.B., K.L. Anderson, M. Caballero, D. Amaya, and J.M. Maroto-Puga: Evaluation of a hand-held electrical conductivity meter for detection of subclinical mastitis in cattle. Am J Vet Res 59(9):1087-1091, 1998.

Anderson, K.L., W.A. Moats, J.E. Rushing, and J. O'Carroll: Detection of milk antibiotic residues by use of screening tests and liquid chromatography after intramammary administration of amoxicillin or penicillin G in cows with clinical mastitis. Am J Vet Res 59(9):1096-1100, 1998.

Musser, J.M.B., K.L. Anderson, and K.L. Tyczkowska: Pharmacokinetic parameters and milk concentrations of ketoprofen after administration as a single intravenous bolus dose to lactating goats. J Vet Pharmacol Ther 21(5):358-363, 1998.

Butler, A., K.L. Anderson, and R. Lyman: Mycoplasmal polyarthritis and septicemia in a herd of goats in North Carolina. Large Anim Pract 19(5):23-25, 1998 (November/December).

Marshall, C.L., and K.L. Anderson: Services provided by and veterinary education of small ruminant practitioners. J Am Vet Med Assoc 208:1983-1986, 1996.

Musser, J.M.B., and K.L. Anderson: Effect of vaccination with an Escherichia coli bacterin-toxoid on milk production in dairy cattle. J Am Vet Med Assoc 209:1291-1293, 1996.