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Beagles Help Researcher Hunt for Genes Associated with Canine, Human Bladder Cancer


The following article by Tracey Peake of the NC State News Bureau originally appeared in the NC State News blog.

Beagles aren’t just one of America’s most popular dog breeds. According to new research from North Carolina State University, they’re also key to new findings about the chromosomal changes associated with urothelial carcinoma, or bladder cancer. These findings could lead to better diagnostic tests for both canine and human patients.

Urothelial carcinoma is the most common form of bladder cancer in both canines and humans, and certain breeds of dogs – beagles, shelties, and several varieties of terrier – are more prone to the disease than others. Over 40,000 new cases of bladder cancer are estimated to occur in the canine population each year (there are approximately 74,000 new cases per year in humans). Since symptoms often mimic those of routine bladder infections and benign lesions, the disease is difficult to catch early.

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