Procedures for obtaining rodents from a non-commercial vendor source for housing in LAR facilities
The process for obtaining rodents from a non-commercial source begins with submission of an Animal Request form to the LAR office by the research staff. The process is facilitated by providing contact information for the shipping institution’s PI (i.e., collaborator), import/export coordinator, and facility veterinarian. The PI is also asked to provide information about any phenotypic abnormalities (e.g., diabetes, immunosuppression, seizures, etc.) which might affect the husbandry, handling, or veterinary care of the animals. If special requirements are necessary for animal care or for hazardous agents, a standard operating procedure will need to be in place for that room.
The LAR office forwards the Animal Request form to the LAR Unit Supervisor and Laboratory Animal Veterinarian. The Unit Supervisor will inquire about husbandry details and receiving dates, in order to ensure appropriate space and LAR facility support upon animal arrival. The Laboratory Animal Veterinarian will coordinate with the Unit Supervisor regarding quarantine location, based upon health status and husbandry practices of the sending institution. Veterinary approval only covers the health issues; space availability dictates final approval for ordering the animals.
The Laboratory Animal Veterinarian will request animal health information from the sending institution. Once the health reports are reviewed, a quarantine plan and budget will be established, and the Principal Investigator contacted. The PI is responsible for the costs incurred during the quarantine, including per diems for the imported animals during quarantine, diagnostic tests, shipping samples, technician time, and purchase and per diems for sentinel animals (or extra colony animals) if needed.
Once the Unit Supervisor and Laboratory Animal Veterinarian give final approval to the shipment request, the PI will be notified of the approval. The LAR office will notify LAR Veterinary Services and the Unit Supervisor of the shipping dates. They will use this information to coordinate any sample collection or sentinel monitoring necessary for the animal order.
The timing for quarantine may vary based on the health status of the colony of origin, ranging from approximately 3 weeks for routine diagnostics to 6-8 weeks if sentinel animals are needed. If test results reveal a cause for concern, the PI will be notified by the Laboratory Animal Veterinarian to discuss options. If favorable diagnostic results are acquired, the Unit Supervisor will be advised to release the animals from quarantine and will notify the PI of the new housing location.
During quarantine, experimental procedures are not allowed, but breeding set-ups may be performed by LAR personnel according to PI instructions. Research staff are not allowed in the quarantine room, unless special arrangements are made and approved by the Laboratory Animal Veterinarian and Unit Supervisor.
Please refer to the “Rodent Housing Policy” on the website for information regarding excluded rodent pathogens. PIs are encouraged to consult with an LAR veterinarian about any aspect of rodent health, including options for rederivation of animals harboring known infectious disease agents.
Revised February 28th, 2012