Dermatology - Autoimmune Focus
Usual Receiving Days:
Dr. Olivry: Monday
Dr. Bizikova: Tuesday, Wednesday
By appointment only
Objectives
Drs. Olivry and Bizikova specialize in the diagnosis and treatment of small animal autoimmune skin diseases, especially pemphigus and other blistering diseases (bullous and mucous membrane pemphigoids, epidermolysis bullosa acquisita). Our dermatology laboratory provides unique support to aid in the diagnosis of autoimmune diseases of animals, with the availability of direct and indirect immunofluorescence assays and identification of the antigen(s) targeted by circulating auto-antibodies. Currently, we are investigating novel modalities for treatment of autoimmune skin diseases such as the use of oral glucocorticoid pulse therapy .
English Bulldog with pemphigus foliaceus before (left) and after (right) immunosuppressive therapy
The presence of anti-basement membrane antibodies (green line) was revealed by indirect immunofluorescence in a dog with epidermolysis bullosa acquisita
In this dog with pemphigus foliaceus, the direct immunofluorescence method allowed to visualize auto-antibody deposition in the skin (fishnet-like green lines)